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Case report
Malignant Deciduoid Mesothelioma (MDM) is an extremely rare variant of epithelioid mesothelioma. It was first described in young females, in the peritoneum, and its relation with asbestos was not well defined.
BMC Clinical Pathology 2017 17:13
Published on: 18 August 2017
Case report
Inflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-...
BMC Clinical Pathology 2017 17:12
Published on: 17 August 2017
Research article
Hereditary non-polyposis colorectal cancer comprises Lynch syndrome and familial colorectal cancer type X (FCCTX). Differences in genetics, demographics and histopathology have been extensively studied. The pu...
BMC Clinical Pathology 2017 17:11
Published on: 17 August 2017
Research article
The pathophysiology and outcome of meningococcal septic shock is closely associated with the plasma level of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating level of meningococcal DNA. Th...
BMC Clinical Pathology 2017 17:10
Published on: 16 August 2017
Case report
Some poorly differentiated thyroid carcinomas (PDTC) arise from pre-existing, well-differentiated carcinomas of follicular cell origin; however, others most likely arise de novo. The case of a PDTC adjacent to a ...
BMC Clinical Pathology 2017 17:9
Published on: 2 June 2017
Research article
As the major subfamily of receptor tyrosine, erythropoietin-producing hepatocellular (Eph) receptor has been related to progression and prognosis in different types of tumors. However, the role and mechanism o...
BMC Clinical Pathology 2017 17:8
Published on: 27 April 2017
Research article
The BD MAX™ Enteric Bacterial Panel (BDM-EBP) is designed and FDA-cleared to detect Salmonella, Shigella, Campylobacter, and Shiga toxin genes stx1/2 from stool samples. However, rectal swabs, which are not FDA-c...
BMC Clinical Pathology 2017 17:7
Published on: 8 April 2017
Technical advance
The growth of tumor cells is accompanied by mutations in nuclear and mitochondrial genomes creating marked genetic heterogeneity. Tumors also contain non-tumor cells of various origins. An observed somatic mit...
BMC Clinical Pathology 2017 17:6
Published on: 8 April 2017
Case report
The coexistence of Rosai-Dorfman disease (RDD) with Langerhans cell histiocytosis (LCH) is very rare, as to date only 17 cases have been reported in the english literature. The pathophysiology of this uncommon...
BMC Clinical Pathology 2017 17:5
Published on: 7 April 2017
Case report
Takostsubo (stress) cardiomyopathy (TC) is a clinical syndrome featuring transient left ventricular dysfunction and wall-motion abnormalities, usually following emotional or physical stress. The diagnosis of T...
BMC Clinical Pathology 2017 17:4
Published on: 5 April 2017
Research article
Urothelial bladder carcinoma (UBC) is one of the most prevalent cancers in men worldwide. Human epidermal growth factor receptor 2 (HER2) expression has been detected in a wide range of urothelial carcinoma. D...
BMC Clinical Pathology 2017 17:3
Published on: 4 April 2017
Research article
Detection of vascular invasion by hematoxylin and eosin staining is the current pathological assessment practice to diagnose breast carcinoma. However, conventional hematoxylin and eosin staining failed to dis...
BMC Clinical Pathology 2017 17:2
Published on: 10 February 2017
Case report
Mycetoma is a chronic granulomatous infectious disease caused by filamentous bacteria or by fungi. The disease is endemic in certain tropical and subtropical areas of the world but can be found elsewhere posin...
BMC Clinical Pathology 2017 17:1
Published on: 2 February 2017
Research article
Advanced genomic techniques such as Next-Generation-Sequencing (NGS) and gene expression profiling, including NanoString, are vital for the development of personalised medicines, as they enable molecular disea...
BMC Clinical Pathology 2016 16:17
Published on: 14 November 2016
Case report
The recent study described a better outcome in acute promyelocytic leukemia patients treated with all-trans retinoic acid and arsenic oxide compared to those treated with all-trans retinoic acid combined with ...
BMC Clinical Pathology 2016 16:16
Published on: 4 October 2016
Research article
Sickle cell disease (SCD) is a class of hemoglobinopathy resulting from a single mutation in the ß-globin chain inducing the substitution of valine for glutamic acid at the sixth amino acid position which lead...
BMC Clinical Pathology 2016 16:15
Published on: 21 September 2016
Research article
Omega-3 long chain-polyunsaturated fatty acids (LC-PUFAs)–docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and eicosapentaenoic acid (EPA)– and omega-6 LC-PUFA arachidonic acid (ARA), are essential for ...
BMC Clinical Pathology 2016 16:14
Published on: 5 August 2016
Research article
Calcifications of atherosclerotic plaques represent a controversial issue as they either lead to the stabilization or rupture of the lesion. However, the cellular key players involved in the progression of the...
BMC Clinical Pathology 2016 16:12
Published on: 29 July 2016
Research article
Podocalyxin-like protein (PODXL) is a cell surface transmembrane glycoprotein, the expression of which has been associated with poor prognosis in a range of malignancies. The aim of this study was to investiga...
BMC Clinical Pathology 2016 16:13
Published on: 29 July 2016
Research article
Effective management of trauma-related invasive fungal wound infections (IFIs) depends on early diagnosis and timely initiation of treatment. We evaluated the utility of routine staining, histochemical stains ...
BMC Clinical Pathology 2016 16:11
Published on: 7 July 2016
Case report
Sebaceous carcinoma (SC) is a rare malignancy, occurring predominantly in eyelids. Till date, only 25 cases of sebaceous carcinoma (SC) of the parotid gland have been reported in world literature.
BMC Clinical Pathology 2016 16:10
Published on: 8 June 2016
Research article
Repeat cytology and HPV testing is used in triage of women with minor cytological lesions. The objective of this study was to evaluate 14-type HPV DNA and 5-type HPV mRNA testing in delayed triage of women wit...
BMC Clinical Pathology 2016 16:9
Published on: 7 June 2016
Case report
Cellular angiofibroma represents a newly described, site specific tumor. Histologically, CAF is a benign mesenchymal neoplasm characterized by two principal components: bland spindle cells and prominent small ...
BMC Clinical Pathology 2016 16:8
Published on: 4 June 2016
Case report
In the spectrum of molecular alterations found in hepatocellular carcinoma (HCC), somatic mutations in the WNT/β-catenin pathway and the p53/cell cycle control pathway are among the most frequent ones. It has ...
BMC Clinical Pathology 2016 16:7
Published on: 1 June 2016
Case report
Primary thyroid lymphoma is an uncommon pathological entity that accounts for only 1 to 5 % of all thyroid malignancies. Primary Burkitt lymphoma of the thyroid gland is very rare. This article presents the fi...
BMC Clinical Pathology 2016 16:6
Published on: 11 May 2016
