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BMC Clinical Pathology

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  1. Content type: Research article

    Gastrointestinal stromal tumors (GIST) are the most common primary mesenchymal tumors of the digestive system. The assessment of their biological behavior still remains a scientific challenge. To date, there a...

    Authors: Boubacar Efared, Gabrielle Atsame-Ebang, Layla Tahiri, Ibrahim Sory Sidibé, Fatimazahra Erregad, Nawal Hammas, Samia Arifi, Ihsane Mellouki, Abdelmalek Ousadden, Khalid Mazaz, Hinde El Fatemi and Laila Chbani

    Citation: BMC Clinical Pathology 2018 18:2

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  2. Content type: Research article

    Measuring expression profiles of inflammatory biomarkers is important in monitoring the polarization of immune responses; therefore, results should be independent of quantitation methods if they are to be acce...

    Authors: Alain Stricker-Krongrad, Catherine Shoemake, Miao Zhong, Jason Liu and Guy Bouchard

    Citation: BMC Clinical Pathology 2018 18:1

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  3. Content type: Research article

    The only potentially curative therapy for myelodysplastic syndrome is allogeneic hematopoietic cell transplant; unfortunately, there is a high relapse rate. The objective of this study was to perform a detaile...

    Authors: Elizabeth L. Courville, Megan Griffith, Celalettin Ustun, Sophia Yohe and Erica Warlick

    Citation: BMC Clinical Pathology 2017 17:28

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  4. Content type: Research article

    Endometrial cancer (EC) is a major health concern due to its rising incidence. Whilst early stage disease is generally cured by surgery, advanced EC has a poor prognosis with limited treatment options. Altered...

    Authors: Ayşe Latif, Amy L. Chadwick, Sarah J. Kitson, Hannah J. Gregson, Vanitha N. Sivalingam, James Bolton, Rhona J. McVey, Stephen A. Roberts, Kay M. Marshall, Kaye J. Williams, Ian J. Stratford and Emma J. Crosbie

    Citation: BMC Clinical Pathology 2017 17:27

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  5. Content type: Research article

    The global prevalence of type 2 diabetes is increasing. Dyslipidaemia is a known complication of diabetes mellitus manifesting frequently as cardiovascular diseases and stoke. Elevation of small, dense low den...

    Authors: Kenneth O. Inaku, Obasola O. Ogunkeye, Fayeofori M. Abbiyesuku, Evelyn K. Chuhwak, Christian O. Isichei, Lucius C. Imoh, Noel O. Amadu and Alexander O. Abu

    Citation: BMC Clinical Pathology 2017 17:26

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  6. Content type: Case report

    Lymphoepithelial carcinoma is a tumor mostly diagnosed in the nasopharynx, but it has also been described in a variety of nonnasopharyngeal sites. It is extremely rare in the larynx and should be distinguished...

    Authors: Nawal Hammas, Najib Benmansour, Mohamed Nour-dine El Alami El Amine, Laila Chbani and Hind El Fatemi

    Citation: BMC Clinical Pathology 2017 17:24

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  7. Content type: Research article

    Intraoperative consultation is an important tool for the evaluation of the upper aerodigestive tract (UAT) malignancies. Although frozen section analysis is a preferred method of intra-operative consultation, ...

    Authors: Hania Naveed, Mariam Abid, Atif Ali Hashmi, Muhammad Muzammamil Edhi, Ahmareen Khalid Sheikh, Ghazala Mudassir and Amir Khan

    Citation: BMC Clinical Pathology 2017 17:25

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  8. Content type: Case report

    Solitary fibrous tumor is an uncommon spindle cell neoplasm of unknown origin. It has been reported in many anatomic sites, with a rare occurrence in the head and neck region. Solitary fibrous tumors of the pa...

    Authors: Meryem Rais, Amine Kessab, Zahra Sayad, Sanae El Mourabit, Redallah Zrarqi, Salma Benazzou, Malik Boulaadas and Nadia Cherradi

    Citation: BMC Clinical Pathology 2017 17:22

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  9. Content type: Case report

    Medulloepithelioma is a rare primitive neuroectodermal tumor of the central nervous system, usually developing in childhood. Due to its rarity, the optimal management is still unknown. The prognosis is poor, e...

    Authors: Nezha Oumghar, Fatima Ezzahra Hazmiri, Abdelhamid El Omrani, Hanane Rais and Mouna Khouchani

    Citation: BMC Clinical Pathology 2017 17:23

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  10. Content type: Case report

    B-cell lymphomas harboring the 8q24/MYC plus 18q21/BCL2 translocations are now referred to as high grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-MBR). Although HGBL-MBR is frequently fo...

    Authors: Akiko Uchida, Yasushi Isobe, Yu Uemura, Yuji Nishio, Hirotaka Sakai, Masayuki Kato, Kaori Otsubo, Masahiro Hoshikawa, Masayuki Takagi and Ikuo Miura

    Citation: BMC Clinical Pathology 2017 17:21

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  11. Content type: Case report

    Primary hyperoxaluria is a rare disease with an estimated prevalence of 1 to 3 cases per million. It is due to a hepatic enzyme deficiency responsible for an endogenous overproduction of oxalate. Oxalate cryst...

    Authors: F. Nachite, M. Dref, A. Fakhri and H. Rais

    Citation: BMC Clinical Pathology 2017 17:20

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  12. Content type: Research article

    Mosquito coil (MC) emits insecticide upon burning which provides limited protection against lethal mosquito borne diseases. However, apart from killing the insect, toxicities associated with the inhalation of ...

    Authors: M. Abdulla Al-Mamun, M. Ataur Rahman, M. Habibur Rahman, K.M.F. Hoque, Z. Ferdousi, Mohammad Nurul Matin and M. Abu Reza

    Citation: BMC Clinical Pathology 2017 17:19

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  13. Content type: Case report

    Primary breast angiosarcoma is defined as malignant proliferation showing endothelial differentiation. It is a very rare tumour (0.05% of primary mammary cancers), whose diagnosis can be difficult.

    Authors: Fayçal Abbad, Najat Cherif Idrissi, Btissam Fatih, Bouchra Fakhir, Jamal Drissi, Mouna Khouchani and Hanane Rais

    Citation: BMC Clinical Pathology 2017 17:17

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  14. Content type: Research article

    Cervical cancer can be prevented by early detection and treatment for precancerous lesions. Since 1995, there has been a national cervical cancer screening program in Norway, where women aged 25–69 years are r...

    Authors: Sveinung Wergeland Sørbye, Pål Suhrke, Berit Wallem Revå, Jannicke Berland, Ramona Johansen Maurseth and Khalid Al-Shibli

    Citation: BMC Clinical Pathology 2017 17:18

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  15. Content type: Research article

    Lumbar puncture with quantification of leukocytes and differential count of cellular subsets in the cerebrospinal fluid is a standard procedure in cases of suspected neuroinfectious conditions. However, a numb...

    Authors: Anne Ahrens Østergaard, Thomas Vognbjerg Sydenham, Mads Nybo and Åse Bengård Andersen

    Citation: BMC Clinical Pathology 2017 17:15

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  16. Content type: Case report

    Ovarian sarcomas represent less than 1% of all ovary cancers and usually are frequent in adults. Primary angiosarcomas are exceptional in the ovaries within children.

    Authors: Tchin Darré, Abdoul-Samadou Aboubakari, Bingo K. N’Bortche, Akila Bassowa, Solange Adani-Ifé and Gado Napo-Koura

    Citation: BMC Clinical Pathology 2017 17:16

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  17. Content type: Research article

    Platelets and coagulation proteins contribute to the development of peripheral arterial disease, especially atherosclerotic disease. Several experimental studies have proven a significant correlation between h...

    Authors: Kimihiro Igari, Toshifumi Kudo, Takahiro Toyofuku and Yoshinori Inoue

    Citation: BMC Clinical Pathology 2017 17:14

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  18. Content type: Case report

    Malignant Deciduoid Mesothelioma (MDM) is an extremely rare variant of epithelioid mesothelioma. It was first described in young females, in the peritoneum, and its relation with asbestos was not well defined.

    Authors: Mouna Khmou, Soumiya Echcharif, Rachad Kabbaj and Basma El Khannoussi

    Citation: BMC Clinical Pathology 2017 17:13

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  19. Content type: Case report

    Inflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-...

    Authors: Adil Boudhas, Mohamed Allaoui, Fouad El Asri, Issam Rharrassi, Mohamed Reda El Ochi, Mohamed Tbouda, Hafsa Chahdi, Abderrahmane Al Bouzidi and Mohamed Oukabli

    Citation: BMC Clinical Pathology 2017 17:12

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  20. Content type: Research article

    Hereditary non-polyposis colorectal cancer comprises Lynch syndrome and familial colorectal cancer type X (FCCTX). Differences in genetics, demographics and histopathology have been extensively studied. The pu...

    Authors: Stefan Haraldsson, Louise Klarskov, Mef Nilbert, Inge Bernstein, Jesper Bonde and Susanne Holck

    Citation: BMC Clinical Pathology 2017 17:11

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  21. Content type: Research article

    The pathophysiology and outcome of meningococcal septic shock is closely associated with the plasma level of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating level of meningococcal DNA. Th...

    Authors: Berit Sletbakk Brusletto, Bernt Christian Hellerud, Else Marit Løberg, Ingeborg Løstegaard Goverud, Åshild Vege, Jens Petter Berg, Petter Brandtzaeg and Reidun Øvstebø

    Citation: BMC Clinical Pathology 2017 17:10

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  22. Content type: Case report

    Some poorly differentiated thyroid carcinomas (PDTC) arise from pre-existing, well-differentiated carcinomas of follicular cell origin; however, others most likely arise de novo. The case of a PDTC adjacent to a ...

    Authors: Hironao Yasuoka, Yasushi Nakamura, Mitsuyoshi Hirokawa, Ken-ichi Yoshida, Kana Anno, Masayuki Tori and Masahiko Tsujimoto

    Citation: BMC Clinical Pathology 2017 17:9

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  23. Content type: Research article

    As the major subfamily of receptor tyrosine, erythropoietin-producing hepatocellular (Eph) receptor has been related to progression and prognosis in different types of tumors. However, the role and mechanism o...

    Authors: Baongoc Nasri, Mikito Inokuchi, Toshiaki Ishikawa, Hiroyuki Uetake, Yoko Takagi, Sho Otsuki, Kazuyuki Kojima and Tatsuyuki Kawano

    Citation: BMC Clinical Pathology 2017 17:8

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  24. Content type: Research article

    The BD MAX™ Enteric Bacterial Panel (BDM-EBP) is designed and FDA-cleared to detect Salmonella, Shigella, Campylobacter, and Shiga toxin genes stx1/2 from stool samples. However, rectal swabs, which are not FDA-c...

    Authors: Barbara DeBurger, Sarah Hanna, Eleanor A. Powell, Cindi Ventrola and Joel E. Mortensen

    Citation: BMC Clinical Pathology 2017 17:7

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  25. Content type: Technical advance

    The growth of tumor cells is accompanied by mutations in nuclear and mitochondrial genomes creating marked genetic heterogeneity. Tumors also contain non-tumor cells of various origins. An observed somatic mit...

    Authors: Paulo Refinetti, Christian Arstad, William G. Thilly, Stephan Morgenthaler and Per Olaf Ekstrøm

    Citation: BMC Clinical Pathology 2017 17:6

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