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Clinical Biochemistry

Section edited by Ferdinando Mannello

This section aims to publish articles covering analysis of bodily fluids. It includes articles relating to clinical chemistry, drug monitoring and toxicology with the focus on laboratory tests. We encourage submission of studies on bodily fluid biomarkers in disease and diagnosis.

  1. Serum cystatin C (SCysC) and serum creatinine (SCr) are two biomarkers used in common practice to estimate the glomerular filtration rate (GFR). For SCysC and SCr to be used in a given population, normal value...

    Authors: Bertille Elodie Edinga-Melenge, Adrienne Tchapmi Yakam, Jobert Richie Nansseu, Catherine Bilong, Suzanne Belinga, Eric Minkala, Prisca Armel Noudjeu, Michel Ondhoua, Samuel Walter Kokola, Vicky Joceline Ama Moor and Gloria Ashuntantang

    Citation: BMC Clinical Pathology 2019 19:4

    Content type: Research article

    Published on:

  2. Vilazodone is an FDA approved medication used to treat major depressive disorder. The authors describe two cases of accidental vilazodone exposure in toddlers who presented with symptoms similar to amphetamine...

    Authors: Christina D. Martinez-Brokaw, Joshua B. Radke, Joshua G. Pierce, Alexandra Ehlers, Sean Ekins, Kelly E. Wood, Jon Maakestad, Jacqueline A. Rymer, Kenichi Tamama and Matthew D. Krasowski

    Citation: BMC Clinical Pathology 2019 19:2

    Content type: Research article

    Published on:

  3. Helicobacter pylori antibody titters fall very slowly even after successful treatment. Therefore, tests detecting H. pylori antibody lack specificity and sensitivity. On the other hand, H. pylori stool antigen te...

    Authors: Markos Negash, Afework Kassu, Bemnet Amare, Gizachew Yismaw and Beyene Moges

    Citation: BMC Clinical Pathology 2018 18:4

    Content type: Research article

    Published on:

  4. Measuring expression profiles of inflammatory biomarkers is important in monitoring the polarization of immune responses; therefore, results should be independent of quantitation methods if they are to be acce...

    Authors: Alain Stricker-Krongrad, Catherine Shoemake, Miao Zhong, Jason Liu and Guy Bouchard

    Citation: BMC Clinical Pathology 2018 18:1

    Content type: Research article

    Published on:

  5. The global prevalence of type 2 diabetes is increasing. Dyslipidaemia is a known complication of diabetes mellitus manifesting frequently as cardiovascular diseases and stoke. Elevation of small, dense low den...

    Authors: Kenneth O. Inaku, Obasola O. Ogunkeye, Fayeofori M. Abbiyesuku, Evelyn K. Chuhwak, Christian O. Isichei, Lucius C. Imoh, Noel O. Amadu and Alexander O. Abu

    Citation: BMC Clinical Pathology 2017 17:26

    Content type: Research article

    Published on:

  6. Platelets and coagulation proteins contribute to the development of peripheral arterial disease, especially atherosclerotic disease. Several experimental studies have proven a significant correlation between h...

    Authors: Kimihiro Igari, Toshifumi Kudo, Takahiro Toyofuku and Yoshinori Inoue

    Citation: BMC Clinical Pathology 2017 17:14

    Content type: Research article

    Published on:

  7. Advanced genomic techniques such as Next-Generation-Sequencing (NGS) and gene expression profiling, including NanoString, are vital for the development of personalised medicines, as they enable molecular disea...

    Authors: Caroline Seiler, Alan Sharpe, J. Carl Barrett, Elizabeth A. Harrington, Emma V. Jones and Gayle B. Marshall

    Citation: BMC Clinical Pathology 2016 16:17

    Content type: Research article

    Published on:

  8. Sickle cell disease (SCD) is a class of hemoglobinopathy resulting from a single mutation in the ß-globin chain inducing the substitution of valine for glutamic acid at the sixth amino acid position which lead...

    Authors: Vicky Jocelyne Ama Moor, Constant Anatole Pieme, Bernard Chetcha Chemegne, Helene Manonji, Borgia Legrand Njinkio Nono, Corine Tchoula Mamiafo, Bruno Moukette Moukette, Francine Tankeu Nzufo and Asonganyi Tazoacha

    Citation: BMC Clinical Pathology 2016 16:15

    Content type: Research article

    Published on:

  9. Omega-3 long chain-polyunsaturated fatty acids (LC-PUFAs)–docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and eicosapentaenoic acid (EPA)– and omega-6 LC-PUFA arachidonic acid (ARA), are essential for ...

    Authors: Grace Mashavave, Patience Kuona, Willard Tinago, Babill Stray-Pedersen, Marshall Munjoma and Cuthbert Musarurwa

    Citation: BMC Clinical Pathology 2016 16:14

    Content type: Research article

    Published on: