Fig. 6

Prediction of chemotherapy effect from IHC. Chemotherapy effect was calculated from RS and plotted against IHC score for each case. Chemotherapy effect was estimated from the model presented by Paik, et al. [13] by subtracting the 10-year likelihood of recurrence at a given RS for patients treated with Tamoxifen + chemotherapy from those treated with Tamoxifen alone. The category to which each sample is assigned based on IHC score is indicated by color; blue = low, green = intermediate, red = high