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Fig. 4 | BMC Clinical Pathology

Fig. 4

From: Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis

Fig. 4

Laser capture microdissected spots with mutants fractions. Marker detected by primer set # 2 is on the top and marker detected by primer set #4 is on the bottom. White is associated with the first peak (homoduplex) in electropherogram, and black is associated with the second peak (homoduplex). The fraction of white and black in each circle, represent the fraction of the first and second variant respectively in each sample. Other color presents mutants not aligning with the internal standard in the electropherogram. Inserted electropherograms represent homoplasmic regions and heteroplasmic areas (e.g., mix of two cell population)

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