Table 1 Extracellular vesicles’ analysis in different tumor types

Bladder cancer

Exosomes from urine contain the angiogenesis-promoting protein EDIL-3

[99]

Breast cancer

Microvesicle numbers and the amount of focal adhesion kinase and EGFR in plasma fractions were associated with different stages of breast cancer

[89]

Colorectal cancer

Proteomic analysis was conducted on EVs from colorectal cancer cells

[103]

Gastric cancer

Proteomic analysis was conducted on EVs from gastric cancer patients

[31]

Glioblastoma

Microvesicle RNA biomarkers of glioblastoma multiforme were identified

[29,55]

Head and neck cancer

Exosomes and microvesicles from patient saliva were used for diagnosis

[104]

Lung cancer

Proteins isolated from microvesicles in pleural effusions due to lung cancer were characterized to identify diagnostic markers

[3]

Melanoma

Proteomic analysis was conducted on exosomes from melanoma patients were used for

[105]

Ovarian cancer

Exosomes from ovarian cancer patients contain different sets of proteins and miRNAs compared to exosomes from normal subjects; the amount of circulating exosomes was 4 times higher in patients

[1,2,92,93,106]

Pancreatic cancer

EVs were used in diagnosing pancreatic cancer

[30]

Prostate cancer

Urine exosomes expressed higher levels of PCA-3 and TMPRSS2-ERG

[58]