Table 2 Variety of mutations associated with RIF and INH resistance (sputum specimens)

RIF resistance pattern ( rpoB gene)

WT probes

Mutant probes

N = 107

Δ8

S531L

93

86.9

Δ8

-

3

2.8

Δ7

H526Y

1

0.9

Δ7

H526D

1

0.9

Δ7,Δ8

-

3

2.8

Δ6

-

2

1.9

Δ3,Δ8

D516V, S531L

1

0.9

Δ3,Δ8

D516V

1

0.9

Δ2,Δ7

-

1

0.9

Δ2,Δ4

-

1

0.9

INH resistance pattern

katG

inhA

WT probes

Mutant probes

WT1 probe

WT2 probe

Mutant probes

N = 117

Δwt

S315T1

WT

WT

-

68

58.1

Δwt

S315T1

WT

WT

C15T

5

4.3

Δwt

S315T1

WT

Δwt

-

2

1.7

Δwt

S315T1

Δwt

WT

C15T

2

1.7

Δwt

S315T1

Δwt

WT

-

2

1.7

Δwt

S315T1, S315T2

WT

WT

-

1

0.9

WT

-

Δwt

WT

C15T

3

2.6

WT

-

WT

WT

C15T

1

0.9

WT

S315T1

WT

WT

-

11

9.4

WT

S315T1

WT

WT

C15T

16

13.7

WT

S315T1

WT

WT

A16G

1

0.9

WT

S315T1

WT

WT

C15T, A16G

3

2.6

WT

S315T1

WT

Δwt

-

1

0.9

WT

S315T1

Δwt

Δwt

-

1

0.9