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Table 2 Sensitivity and specificity of HIV testing on sputum at various days, with and without CPC

From: Low specificity of HIV-testing on sputum specimens kept at ambient temperatures for 4 to 7 days: a blinded comparison

 

HIV serum ELISA (Standard)

  

HIV on sputum

Positive

Negative

Sensitivity (95% CI)

Specificity (95% CI)

Day 1

  

94.7% (89.4–97.8%)

92.9% (88.9–95.8%)

Positive

125

7

  

Negative

7

233

  

Total

132

240

  

Without CPC

Day 4

  

93.2% (87.5–96.8%)

76.7% (70.9–81.9%)

Positive

123

56

  

Negative

9

185

  

Total

132

241

  

Day 7

  

92.9% (87.0–96.7%)

62.7% (55.5–69.5%)

Positive

118

72

  

Negative

9

121

  

Total

127

193

  

With CPC

Day 4

  

93.9% (87.3–97.7%)

67.8% (60.4–74.5%)

Positive

93

58

  

Negative

6

122

  

Total

99

180

  

Day 7

  

94.9% (87.5–97.9%)

49.6% (40.5–58.7%)

Positive

94

63

  

Negative

5

62

  

Total

99

125