Table 1 Cox regression analysis summarizing significant independent prognostic factors
Factor | HR | 95% CI | P |
|---|---|---|---|
Tumor status | 0.002* | ||
1 | 1.00 | ||
2 | 1.54 | 0.91 – 2.59 | 0.108 |
3 | 2.73 | 1.53 – 4.90 | 0.001 |
Nodal status | <0.001* | ||
0 | 1.00 | ||
1 | 1.98 | 1.27 – 3.08 | 0.003 |
2 | 3.13 | 1.80 – 5.46 | <0.001 |
Histology | |||
SCC | 1.00 | ||
Other NSCLC | 0.99 | 0.500 – 1.98 | 0.986 |
Differentiation | 0.094* | ||
Poor | 1.00 | ||
Moderate | 0.70 | 0.46 – 1.05 | 0.083 |
Well | 0.56 | 0.29 – 1.10 | 0.095 |
Performance status | |||
ECOG = 0 | 1.00 | ||
ECOG = 1-2 | 1.80 | 1.23 – 2.64 | 0.003 |
Vascular infiltration | |||
No | 1.00 | ||
Yes | 1.82 | 1.12 – 2.98 | 0.016 |
Dicer** | 0.87 | 0.65 – 1.16 | 0.333 |
Dicer*Histology*** | 1.27 | 1.00 – 1.61 | 0.049 |
Drosha / miR-126 | 0.033* | ||
Low / Low | 1.00 | ||
Low / High | 1.13 | 0.62 – 2.05 | 0.696 |
High / Low | 0.63 | 0.37 – 1.07 | 0.089 |
High / High | 1.96 | 1.04 – 3.69 | 0.037 |