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Table 1 Cox regression analysis summarizing significant independent prognostic factors

From: Prognostic value of the MicroRNA regulators Dicer and Drosha in non-small-cell lung cancer: co-expression of Drosha and miR-126 predicts poor survival

Factor HR 95% CI P
Tumor status    0.002*
 1 1.00   
 2 1.54 0.91 – 2.59 0.108
 3 2.73 1.53 – 4.90 0.001
Nodal status    <0.001*
 0 1.00   
 1 1.98 1.27 – 3.08 0.003
 2 3.13 1.80 – 5.46 <0.001
Histology    
 SCC 1.00   
 Other NSCLC 0.99 0.500 – 1.98 0.986
Differentiation    0.094*
 Poor 1.00   
 Moderate 0.70 0.46 – 1.05 0.083
 Well 0.56 0.29 – 1.10 0.095
Performance status    
 ECOG = 0 1.00   
 ECOG = 1-2 1.80 1.23 – 2.64 0.003
Vascular infiltration    
 No 1.00   
 Yes 1.82 1.12 – 2.98 0.016
Dicer** 0.87 0.65 – 1.16 0.333
Dicer*Histology*** 1.27 1.00 – 1.61 0.049
Drosha / miR-126    0.033*
 Low / Low 1.00   
 Low / High 1.13 0.62 – 2.05 0.696
 High / Low 0.63 0.37 – 1.07 0.089
 High / High 1.96 1.04 – 3.69 0.037
  1. *Overall significance as a prognostic factor.
  2. **B = −0.141.
  3. ***B = 0.240.
  4. Dicer*Histology = the interaction between Dicer and Histology.
  5. HR: Hazard ration; CI: confidence interval.