Figure 1

Primary ciliogenesis progresses through five morphologically distinct stages in human astrocytes. Key characteristics of each stage are indicated with arrows. Paired lateral vesicles are prominent at the distal end of the basal body in Stage 1. Distal appendages are triangular in appearance and reside at the distal end of the basal body (Stage 2). The paired lateral vesicles fuse to become a vesicular hat and become stretched by the outgrowth of the primary cilium and can be seen progressing through stages 2 through 4. Stage 5 shows a mature primary cilium with a surrounding cilium-pit. Used with permission from Moser et al. BMC Cancer 2009, 9:448, Figure 2 A © BioMed Central.