Table 3 Clinicopathologic variables as predictors for 5-year disease-specific death in univariate analysis for 80 patients with OSCC
Patients (N = 80) | 5-Year death (%) | P-value | |
|---|---|---|---|
(no. (%)) | |||
Gender | |||
Male | 46 (57.5) | 37.0 | 0.403 |
Female | 34 (42.5) | 29.4 | |
Age at diagnosis, years | |||
0-59 | 29 (36.3) | 31.0 | 0.637 |
≥ 60 | 51 (63.8) | 35.3 | |
Smoking history | |||
Never smoker | 18 (22.5) | 27.8 | |
Former smoker | 11 (13.8) | 27.3 | 0.897 |
Current smoker | 45 (56.3) | 37.3 | |
Unknown | 6 (7.5) | 33.3 | |
Alcohol consumption | |||
Never | 13 (16.3) | 23.1 | |
≤ 1 times weekly | 30 (37.5) | 33.3 | 0.633 |
> 1 times weekly or daily | 20 (25.0) | 35.0 | |
Unknown | 17 (21.3) | 41.2 | |
Tumour site | |||
Mobile tongue | 38 (47.5) | 21.1 | |
Floor of mouth | 22 (27.5) | 40.9 | 0.074 |
All others* | 20 (25.0) | 50.0 | |
Tumour differentiation | |||
Well | 30 (37.5) | 26.7 | |
Moderate | 44 (55.0) | 36.4 | 0.296 |
Poor | 6 (7.5) | 50.0 | |
T stage** | |||
T1 | 29 (36.7) | 20.7 | |
T2 | 27 (34.2) | 11.1 | <0.001 |
T3, T4 | 23 (29.1) | 78.3 | |
N stage | |||
N0 | 54 (67.5) | 22.2 | |
N+ | 20 (25.0) | 70.0 | <0.001 |
Unknown | 6 (7.5) | 16.7 | |
M stage | |||
M0 | 74 (92.5) | 33.8 | |
M+ | 1 (1.3) | 100.0 | 0.021 |
Unknown | 5 (6.3) | 20.0 | |
HPV/p16 | |||
Negative | 68 (85.0) | 35.3 | |
Positive | 6 (7.5) | 16.7 | 0.720 |
Unknown | 6 (7.5) | 33.3 | |
TLS single level | |||
Negative | 67 (83.8) | 37.3 | 0.156 |
Positive | 13 (16.3) | 15.4 | |
TLS multiple level | |||
Negative | 63 (78.8) | 39.7 | 0.039 |
Positive | 17 (21.3) | 11.8 |