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Table 5 Distribution of examined markers according to subtypes

From: alphaB-crystallin is a marker of aggressive breast cancer behavior but does not independently predict for patient outcome: a combined analysis of two randomized studies

 

Luminal A

Luminal B

Luminal-HER2

HER2-enriched

TNBC

BCP

 

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

alphaB-crystallin

      

 Negative

213 (93.4)

299 (80.6)

109 (83.8)

88 (88.0)

61 (55.0)

41 (48.2)

 Weakly positive

8 (3.5)

40 (10.8)

16 (12.3)

11 (11.0)

24 (21.6)

19 (22.4)

 Strongly positive

7 (3.1)

32 (8.6)

5 (3.8)

1 (1.0)

26 (23.4)

25 (29.4)

BRCA1

      

 Negative

206 (92.0)

334 (91.0)

125 (97.7)

95 (95.0)

103 (94.5)

79 (92.9)

 Positive

18 (8.0)

33 (9.0)

3 (2.3)

5 (5.0)

6 (5.5)

6 (7.1)

BRCA1

      

 WT

19 (90.5)

27 (100.0)

11 (100.0)

10 (100.0)

11 (64.7)

9 (60.0)

 Mutated

2 (9.5)

0

0

0

6 (35.3)

6 (40.0)

p53

      

 Negative

148 (67.3)

154 (42.1)

56 (43.8)

41 (42.3)

46 (43.0)

32 (38.6)

 Positive

72 (32.7)

212 (57.9)

72 (56.3)

56 (57.7)

61 (57.0)

51 (61.4)

  1. N, number; TNBC, triple-negative breast cancer; BCP, basal core phenotype; WT, wild-type.