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Table 2 Uni- and multivariate analyses using Cox proportional hazards model

From: Ki-67 is a strong prognostic marker of non-small cell lung cancer when tissue heterogeneity is considered

 

Univariate

Multivariate

HR

P-value

HR

P-value

NSCLC (n = 74)

Age

1.021

0.2997

1.014

0.5763

Gender

1.671

0.1864

1.431

0.3777

Stage

1.750

< 0.0001

1.432

0.0002

HS

8.702

< 0.0001

5.497

0.0001

ADC (n = 47)

Age

1.033

0.2118

1.004

0.9044

Gender

1.489

0.3701

1.990

0.1633

Stage

15.614

< 0.0001

1.705

0.0024

HS

7.025

< 0.0001

4.424

0.0050

SqCC (n = 27)

Age

0.999

0.9942

1.05

0.3197

Gender

1934

0.2834

1.048e + 10

0.2611

Stage

12.295

0.0055

1.188

0.3096

HS

1.41e + 9

0.0002

1.44e + 10

0.0011

  1. NSCLC, non-small cell lung cancer; ADC, adenocarcinoma; SqCC, squamous cell carcinoma; HS, highest score. Significant P-values are shown in Italics. P-values from log-rank test.