Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas

BMC Clinical Pathology

Table 5 Co-expression of Skp2/ER, Skp2/PGR and their prediction for disease-specific survival in patients with soft tissue sarcomas (univariate analysis; log-rank test), All = 193, Men = 81, Women = 112

Co-expression	Patients (n)	Patients (%)	Median survival (months)	5-Year survival (%)	P
Skp2 / ER, all
Low/low	66	34	NR	67	0.049
Low/high	39	20	91	59
High/low	35	18	57	44
High/high	30	16	NR	58
Missing	23	12
Skp2 / ER, men
Low/low	33	41	NR	72	0.427
Low/high	16	20	37	50
High/low	11	14	NR	72
High/high	11	14	63	58
Missing	10	12
Skp2 / ER, women
Low/low	33	29	127	61	0.021
Low/high	23	21	91	65
High/low	24	21	31	32
High/high	19	17	NR	58
Missing	13	12
Skp2 / PGR, all
Low/low	80	41	NR	71	0.056
Low/high	25	13	54	46
High/low	40	21	59	49
High/high	27	14	67	51
Missing	21	11
Skp2 / PGR, men
Low/low	41	51	NR	73	0.141
Low/high	7	9	26	29
High/low	18	22	NR	61
High/high	5	6	67	60
Missing	10	12
Skp2 / PGR, women
Low/low	39	35	NR	68	0.234
Low/high	18	16	75	54
High/low	22	20	29	39
High/high	22	20	57	49
Missing	11	10

ISSN: 1472-6890