Table 2 Uni- and multivariate analyses
From: Metabolic markers GAPDH, PKM2, ATP5B and BEC-index in advanced serous ovarian cancer
Expression | Univariate analysis | Multivariate analysisa | ||||
|---|---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |||
GAPDH | PFI | low (<0.25), n = 18 | 1 | 1 | ||
high (≥0.25), n = 37 | 2.1 (1.1-4.0) | 0.031 | 2.1 (1.0-4.5) | 0.043 | ||
OS | low (<0.25), n = 18 | 1 | 1 | |||
high (≥0.25), n = 37 | 2.8 (1.2-6.5) | 0.015 | 2.3 (1.0-5.6) | 0.063 | ||
PKM2 | PFI | low (<0.70), n = 18 | 1 | 1 | ||
high (≥0.70), n = 37 | 1.2 (0.7-2.3) | 0.55 | 1.5 (0.8-2.8) | 0.27 | ||
OS | low (<0.70), n = 18 | 1 | 1 | |||
high (≥0.70), n = 37 | 1.1 (0.5-2.2) | 0.87 | 1.2 (0.6-2.6) | 0.60 | ||
ATP5B | PFI | low (<0.31), n = 18 | 1 | 1 | ||
high (≥0.31), n = 37 | 1.7 (0.9-3.3) | 0.089 | 1.8 (0.9-3.6) | 0.097 | ||
OS | low (<0.31), n = 18 | 1 | 1 | |||
high (≥0.31), n = 37 | 2.6 (1.1-5.9) | 0.025 | 2.3 (1.0-5.3) | 0.062 | ||
BEC-index | PFI | low (≤2.65), n = 36 | 1 | 1 | ||
high (>2.65), n = 19 | 0.46 (0.23-0.92) | 0.028 | 0.47 (0.23-0.95) | 0.035 | ||
OS | low (≤2.65), n = 36 | 1 | 1 | |||
high (>2.65), n = 19 | 0.42 (0.20-0.94) | 0.033 | 0.49 (0.22-1.31) | 0.088 | ||