Table 4 Analysis of IHC expression of Integrins expression according to covariates in patients with CRC (n = 114)

Age

< 60 years

27/29

0.259

27/29

1.00

49/7

<0.001

30/26

1.000

30/26

0.851

≥ 60 years

35/23

28/30

4/54

31/27

33/25

Gender

Male

34/29

1.000

28/35

0.451

29/34

1.000

36/27

0.452

35/28

1.00

Female

28/23

27/24

24/27

25/26

28/23

Histological type

Adeno

54/43

0.601

48/49

0.502

51/ 46

0.003

61/36

0.002

53/44

0.684

Mucinous

8/9

7/10

2/15

0/17

10/7

Tumor grading

Low grade

56/44

0.401

50/50

0.397

48/52

0.569

57/43

0.083

57/43

0.394

High grade

6/8

5/9

5/9

4/10

6/8

Venous invasion

Absent

58/35

<0.001

52/41

0.001

42/51

0.631

61/32

<0.001

54/39

0.239

Present

4/17

3/18

11/10

0/21

09/12

Perineural invasion

Absent

62/44

0.001

52/54

0.781

49/57

1.000

59/47

0.142

60/46

0.464

Present

0/8

3/5

4/4

2/6

3/5

Clinical stage

I-II

59/5

<0.001

53/11

<0.001

28/36

0.572

40/24

0.038

49/15

<0.001

III- IV

3/47

2/48

25/25

21/29

14/36