Skip to main content

Table 4 Analysis of IHC expression of Integrins expression according to covariates in patients with CRC (n = 114)

From: Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma

Covariates Categorization Integrins
αV α3 α5 α6 β5
- / + p - / + p - / + p - / + p - / + p
Age < 60 years 27/29 0.259 27/29 1.00 49/7 <0.001 30/26 1.000 30/26 0.851
≥ 60 years 35/23   28/30   4/54   31/27   33/25  
Gender Male 34/29 1.000 28/35 0.451 29/34 1.000 36/27 0.452 35/28 1.00
Female 28/23   27/24   24/27   25/26   28/23  
Histological type Adeno 54/43 0.601 48/49 0.502 51/ 46 0.003 61/36 0.002 53/44 0.684
Mucinous 8/9   7/10   2/15   0/17   10/7  
Tumor grading Low grade 56/44 0.401 50/50 0.397 48/52 0.569 57/43 0.083 57/43 0.394
High grade 6/8   5/9   5/9   4/10   6/8  
Venous invasion Absent 58/35 <0.001 52/41 0.001 42/51 0.631 61/32 <0.001 54/39 0.239
Present 4/17   3/18   11/10   0/21   09/12  
Perineural invasion Absent 62/44 0.001 52/54 0.781 49/57 1.000 59/47 0.142 60/46 0.464
Present 0/8   3/5   4/4   2/6   3/5  
Clinical stage I-II 59/5 <0.001 53/11 <0.001 28/36 0.572 40/24 0.038 49/15 <0.001
III- IV 3/47   2/48   25/25   21/29   14/36  
  1. -/+ = Low/high expression; Adeno.,Adenocarcinoma. Significant values are bold.
\