Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas

BMC Clinical Pathology

Table 2 Expression of markers in tumor and their prediction for disease-specific survival in patients with soft tissue sarcomas (univariate analysis; log-rank test), N = 249

Marker expression	Patients (n)	Patients (%)	Median survival (months)	5-Year survival (%)	P
CD 57
Low	93	37	54	49	0.617
High	135	54	49	48
Missing	21	8
CD 68
Low	57	23	91	52	0.270
High	172	69	45	47
Missing	20	8
M-CSF
Low	56	22	NR	59	0.034
High	169	68	38	44
Missing	24	10
CSF-1R
Low	38	15	41	44	0.832
High	191	77	38	46
Missing	20	8
Ki67
Low	31	12	NR	63	<0.001
Medium	63	25	NR	59
High	139	56	24	37
Missing	16	6
TGF-beta
Low	117	47	99	53	0.003
High	122	49	29	37
Missing	10	4
M-CSF and TGF-beta
Low	119	48	91	53	0.004
High	101	41	29	38
Missing	29	12

ISSN: 1472-6890