Figure 1
From: Mitochondrial mosaics in the liver of 3 infants with mtDNA defects
Patient 1, brain MRI. 1a: TRACE sequence shows cytotoxic oedema in frontoparietal white matter bilaterally, and in right occipital. 1b: FLAIR sequence, right occipital and bilateral frontoparietal lesions; compare to fig 1a. 1c: 5 months later. T1 weighted without iv contrast. Bifrontal white matter loss with lacunae, small lacuna in right occipital. 1d: Coronal section; bilateral loss of white matter; lacunae lined by high signal interpreted as gliosis.