Table 1 pThr187-p27, "plain"-p27 and MIB-1 expression in normal tissues.
From: p27Kip1 is expressed in proliferating cells in its form phosphorylated on threonine 187
Tissue type | Phospho-p27 | "plain"-p27 | MIB-1 |
|---|---|---|---|
Normal squamous epithelium skin, tonsil, larynx, cervix. | |||
Parabasal layer | +++ | - | ++++ |
intermediate | - | ++++ | + |
Granular layer | - | +++ | - |
Germinal centers Tonsil, lymphnode, apendix | |||
Mantle cells | - | ++++ | - |
Centroblasts | +++ | - | ++++ |
Centrocytes | - | +++ | - |
Bowel Crypt cells | |||
Deep | +++ | - | ++++ |
superficial | - | ++++ | - |
Placenta | |||
trophoblast | +++ | - | ++++ |
syncytiotrofoblast | - | ++++ | - |
Kidney | +/- | +++ | +/- |
Lung | +/- | +++ | +/- |
Thyroid | +/- | +++ | +/- |
Prostate | +/- | +++ | +/- |