Total | Genoptix | Large Labs | Other Controls | p-value | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Study population size | (N = 24,664) | (N = 1,387) | (N = 4,162) | (N = 19,115) | ||||||
n | % | n | % | n | % | n | % | |||
Suspected diagnoses | MDS | 859 | 3.48 | 23 | 1.66 | 128 | 3.08 | 708 | 3.70 | <0.001 |
MPN | 1,004 | 4.07 | 61 | 4.40 | 159 | 3.82 | 784 | 4.10 | 0.578 | |
CLL | 816 | 3.31 | 38 | 2.74 | 126 | 3.03 | 652 | 3.41 | 0.217 | |
MM | 1,507 | 6.11 | 68 | 4.90 | 198 | 4.76 | 1,241 | 6.49 | <0.001 | |
NHL | 4,894 | 19.84 | 215 | 15.50 | 814 | 19.56 | 3,865 | 20.22 | <0.001 | |
Other hematologic cancer | 2,787 | 11.30 | 53 | 3.82 | 253 | 6.08 | 2,481 | 12.98 | <0.001 | |
Other hematologic conditions | 13,815 | 56.01 | 932 | 67.20 | 2,537 | 60.96 | 10,346 | 54.13 | <0.001 | |
Gender | Male | 12,979 | 52.62 | 687 | 49.53 | 2,199 | 52.84 | 10,093 | 52.80 | 0.060 |
Female | 11,685 | 47.38 | 700 | 50.47 | 1,963 | 47.16 | 9,022 | 47.20 | 0.060 | |
Age group | 0-17 | 872 | 3.54 | 0 | 0.00 | 20 | 0.48 | 852 | 4.46 | <0.001 |
18-44 | 3,813 | 15.46 | 226 | 16.29 | 681 | 16.36 | 2,906 | 15.20 | 0.117 | |
45-64 | 10,272 | 41.65 | 636 | 45.85 | 1,911 | 45.92 | 7,725 | 40.41 | <0.001 | |
65+ | 9,707 | 39.36 | 525 | 37.85 | 1,550 | 37.24 | 7,632 | 39.93 | 0.003 | |
Insurance type | Commercial | 18,639 | 75.57 | 1,068 | 77.00 | 3,280 | 78.81 | 14,291 | 74.76 | <0.001 |
Medicare | 6,025 | 24.43 | 319 | 23.00 | 882 | 21.19 | 4,824 | 25.24 | <0.001 | |
Baseline therapy | Pre-index chemotherapy | 1,908 | 7.74 | 83 | 5.98 | 291 | 6.99 | 1,534 | 8.03 | 0.003 |
Pre-index radiation therapy | 1,556 | 6.31 | 70 | 5.05 | 240 | 5.77 | 1,246 | 6.52 | 0.027 | |
History of radiation therapy | 71 | 0.29 | 2 | 0.14 | 8 | 0.19 | 61 | 0.32 | 0.226 | |
Geographical distribution | Northeast | 2,391 | 9.69 | 62 | 4.47 | 512 | 12.30 | 1,817 | 9.51 | <0.001 |
Midwest | 6,945 | 28.16 | 104 | 7.50 | 667 | 16.03 | 6,174 | 32.30 | <0.001 | |
South | 11,882 | 48.18 | 1,027 | 74.04 | 2,660 | 63.91 | 8,195 | 42.87 | <0.001 | |
West and other | 3,442 | 13.96 | 193 | 13.91 | 322 | 7.74 | 2,927 | 15.31 | <0.001 | |
Unknown | 4 | 0.02 | 1 | 0.07 | 1 | 0.02 | 2 | 0.01 | 0.200 | |
Presence of down’s syndrome | 31 | 0.13 | 1 | 0.07 | 1 | 0.02 | 29 | 0.15 | 0.092 | |
Age (in years) | Mean (SD) | 58.49 | (18.04) | 59.88 | (15.12) | 59.39 | (15.46) | 58.19 | (18.73) | <0.001 |
Median | 60.00 | 60.00 | 60.00 | 60.00 | ||||||
Pre-index Quan-Charlson comorbidity score | Mean (SD) | 2.18 | (2.11) | 2.08 | (2.11) | 2.04 | (2.01) | 2.22 | (2.13) | <0.001 |
Median | 2.00 | 2.00 | 2.00 | 2.00 | ||||||
Distance to MSA | Mean (SD) | 3.09 | (11.73) | 2.96 | (10.26) | 2.25 | (10.26) | 3.28 | (12.11) | <0.001 |
Median | 0.00 | 0.00 | 0.00 | 0.00 |