From: Central nervous system tumors: a single center pathology review of 34,140 cases over 60 years
 | N (%) | M | F | Ma(yrs) | Ma(yrs) |
---|---|---|---|---|---|
I. Tumors of neuroepithelial tissue | |||||
  1. Astrocytic tumors | |||||
   Pilocytic astrocytoma | 469 (1.69) | 253 | 214 | 21.1 | 17 |
   Pilomyxoid astrocytoma | 20 (0.07) | 8 | 12 | 19.2 | 17 |
   Subependymal giant cell astrocytoma | 27 (0.10) | 15 | 12 | 16.2 | 13 |
   Pleomorphic xanthoastrocytoma | 67 (0.24) | 33 | 34 | 28.4 | 23 |
   Glioblastoma | 2170 (7.81) | 1362 | 805 | 50.2 | 53 |
   Giant cell glioblastoma | 12 (0.04) | 9 | 3 | 42.7 | 41 |
   Gliosarcoma | 64 (0.23) | 39 | 25 | 48.8 | 50.5 |
   Anaplastic astrocytoma | 939 (3.38) | 593 | 346 | 49.2 | 42 |
   Gliomatosis cerebri | 3 (0.01) | 2 | 1 | 59 | 62 |
  2. Oligodendroglial tumors | |||||
   Oligodendroglioma | 990 (3.56) | 555 | 426 | 38.6 | 39 |
   Anaplastic oligodendrogliom | 534 (1.92) | 313 | 221 | 43.5 | 44 |
  3. Oligoastrocytic tumors | |||||
   Oligoastrocytoma | 243 (0.87) | 143 | 100 | 38.9 | 39 |
   Anaplastic oligoastrocytoma | 89 (0.32) | 56 | 33 | 44.7 | 46 |
  4. Ependymal tumors | |||||
   Ependymoma | 623 (2.24) | 350 | 273 | 37 | 38 |
   Subependymoma | 39 (0.14) | 21 | 18 | 43 | 43 |
   Anaplastic ependymoma | 223 (0.80) | 129 | 93 | 30 | 30 |
  5. Choroid plexus tumor | |||||
   Choroid plexus papilloma | 91 (0.33) | 34 | 57 | 29 | 29 |
   Atypical choroid plexus papilloma | 2 (0.01) | 0 | 2 | 37.5 | 37.5 |
   Choroid plexus carcinoma | 11 (0.04) | 8 | 3 | 31.6 | 25 |
  6. Other neuroepithelial tumors | |||||
   Chordoid glioma of the third ventricle | 3 (0.01) | 1 | 2 | 31.3 | 27 |
   Astroblastoma | 4 (0.01) | 2 | 2 | 37.8 | 42 |
  7. Neuronal and mixed neuronal-glial tumors | |||||
   Cerebellar liponeurocytoma | 1 (0.00) | 1 | 0 | 59 | 59 |
   Desmoplastic infantile astrocytoma/ganglioglioma | 5 (0.02) | 1 | 4 | 16.8 | 11 |
   Dysembryoplastic neuroepithelial tumor | 54 (0.19) | 34 | 20 | 22.6 | 17.5 |
   Dysplastic gangliocytoma of cerebellum, Lhermitte-Duclos | 7 (0.03) | 3 | 4 | 28.7 | 38 |
   Rosette-forming glioneuronal tumor of the fourth ventricle | 4 (0.01) | 0 | 4 | 28.3 | 24 |
   Paraganglioma | 29 (0.10) | 14 | 15 | 42.5 | 42 |
   Papillary glioneuronal tumor | 13 (0.05) | 9 | 4 | 32.4 | 29 |
   Anaplastic ganglioglioma | 43 (0.15) | 26 | 17 | 39.7 | 41 |
   Gangliocytoma | 40 (0.14) | 29 | 11 | 29.6 | 31.5 |
   Ganglioglioma | 137 (0.49) | 87 | 49 | 33.1 | 32 |
   Central neurocytoma | 131 (0.47) | 63 | 68 | 30.2 | 29 |
  8. Tumors of pineal region | |||||
   Papillary tumor of the pineal region | 2 (0.01) | 1 | 1 | 31.5 | 31.5 |
   Pineocytoma | 15 (0.05) | 5 | 10 | 30.3 | 22 |
   Pineal parenchymal tumor of intermediate differentiation | 5 (0.02) | 5 | 0 | 26.8 | 20 |
   Pineoblastoma | 10 (0.04) | 5 | 5 | 25.6 | 17.5 |
  9. Embryonal tumors | |||||
   Medulloblastoma | 515 (1.85) | 329 | 183 | 15.4 | 12 |
   PNET | 119 (0.43) | 75 | 43 | 21.9 | 17 |
   Atypical teratoid/rhabdoid tumor | 4 (0.01) | 2 | 2 | 21.8 | 23 |
II. Tumors of cranial and paraspinal nerves | |||||
  1. Schwannoma (neurilemoma, neurinoma) | 3499 (12.59) | 1754 | 1736 | 45 | 45 |
  2. Neurofibroma | 166 (0.60) | 106 | 60 | 36.3 | 38 |
  3. Perineurioma | 1 (0.00) | 0 | 1 | 69 | 69 |
  4. MPNST | 26 (0.09) | 11 | 15 | 37.8 | 42 |
III. Tumors of meninges | |||||
  1. Tumors of meningothelial cells | |||||
   Grade I meningothelial cells tumors | 7623 (27.42) | 2294 | 5309 | 50.7 | 51 |
   Atypical | 359 (1.29) | 184 | 173 | 51.2 | 52 |
   Chordoid | 16 (0.06) | 8 | 8 | 48.5 | 51 |
   Clear cell | 30 (0.11) | 13 | 17 | 37.5 | 39.5 |
   Papillary | 26 (0.09) | 16 | 10 | 36.7 | 35.5 |
   Rhabdoid | 15 (0.05) | 9 | 6 | 42.2 | 42 |
   Anaplastic, malignant | 235 (0.85) | 129 | 105 | 50.3 | 50 |
  2. Mesenchymal tumors | |||||
   Hemangiopericytoma | 202 (0.73) | 112 | 88 | 43.3 | 42 |
   Anaplstic hemangiopericytoma | 8 (0.03) | 5 | 3 | 48.3 | 45.5 |
   Other Mesenchymal tumors | 825 (2.97) | 450 | 369 | 36 | 37 |
  3. Primarymelanocytic lesions | |||||
   Diffuse melanocytosis | 2 (0.01) | 1 | 1 | 35.5 | 35.5 |
   Melanocytoma | 9 (0.03) | 5 | 4 | 47 | 47 |
   Malignantmelanoma | 31 (0.11) | 21 | 10 | 42.2 | 42 |
  4. Other neoplasms related to the meninges | |||||
   Hemangioblastoma | 760 (2.73) | 463 | 293 | 40.8 | 40 |
IV. Lymphomas and hematopoietic neoplasms | 464 (1.67) | 272 | 191 | 49.7 | 52 |
V. Germ cell tumors | |||||
  1. Germinoma | 204 (0.73) | 148 | 56 | 17.4 | 16 |
  2. Embryonal carcinoma | 14 (0.05) | 12 | 2 | 12.2 | 12.5 |
  3. Yolk sac tumor | 2 (0.01) | 2 | 0 | 7 | 7 |
  4. Choriocarcinoma | 1 (0.00) | 0 | 1 | 34 | 34 |
  5. Teratoma | 10 (0.04) | 8 | 2 | 14.5 | 14 |
   Mature | 56 (0.20) | 36 | 20 | 23.5 | 20.5 |
   Immature | 22 (0.08) | 20 | 2 | 16 | 14.5 |
   With malignant transformation | 4 (0.01) | 4 | 0 | 13.3 | 14 |
  6. Mixed germ cell tumors | 35 (0.13) | 29 | 6 | 16.6 | 14 |
VI. Tumors of the sellar region | |||||
   Craniopharyngioma | 1144 (4.11) | 665 | 477 | 32.1 | 33 |
   Granular cell tumor | 7 (0.03) | 2 | 5 | 49 | 52 |
   Pituicytoma | 1 (0.00) | 1 | 0 | 45 | 45 |
   Spindle cell oncocytoma of the adenohypophysis | 1 (0.00) | 1 | 0 | 24 | 24 |
VII. Metastatic tumors | 1431 (5.15) | 890 | 536 | 53.9 | 55 |
Total | 27802 | 13945 | 13774 | Â | Â |