| | Mean | N | Std. Deviation |
---|
HER2/CEN-17 ratio |
HER2 CISH | 1.28 | 320 | 0.28 |
|
HER2 FISH | 1.27a
| 317 | 0.35 |
| PathVysion | 1.28b
| 319 | 0.40 |
HER2 signals |
HER2 CISH | 55.36 | 320 | 20.62 |
|
HER2 FISH | 50.90c
| 317 | 20.59 |
| PathVysion | 50.59d
| 319 | 26.09 |
CEN-17 signals |
HER2 CISH | 42.95 | 320 | 11.44 |
|
HER2 FISH | 40.35e
| 317 | 12.28 |
| PathVysion | 39.52f
| 319 | 14.75 |
- Signal copy numbers were normalized to 20 nuclei
- a) Not significantly different from CISH ratio in a two tailed, paired t-test (N = 316, P = 0.326)
- b) Not significantly different from CISH ratio in a two tailed, paired t-test (N = 318, P = 0.982)
- c) Significantly different from CISH HER2 signals in a two tailed, paired t-test (N = 316, P < 0.001)
- d) Significantly different from CISH HER2 signals in a two-tailed, paired t-test (N = 318, P < 0.001)
- e) Significantly different from CISH CEN-17 signals in a two tailed, paired t-test (N = 316, P < 0.001)
- f) Significantly different from CISH CEN-17 signals in a two-tailed, paired t-test (N = 318, P < 0.001)