| | PathVysion HER-2 FISH | |
---|
| | Non-amplified | Amplified | Total |
---|
HER2 CISH pharmDx™ | Non-amplified | 302 | 4 | 306 |
| Amplified | 4 | 40 | 44 |
| Total | 306 | 44 | 350 |
- Two tailed 95% confidence intervals are based on the binomial distribution. Overall agreement: (342/350 × 100) = 97.7% (CI95: 95.7%; 98.9%), Positive agreement: (40/44 × 100) = 90.9% (CI95: 79.8%; 96.9%), Negative agreement: (302/306 × 100) = 98.7% (CI95: 96.9%; 99.6%) and Kappa: 0.90 (SE: 0.04)