BMC Clinical Pathology

Table 3 Cross tabulation of HER2 gene status for CISH versus Dako FISH.

From: Dual color chromogenic in situ hybridization for determination of HER2 status in breast cancer: a large comparative study to current state of the art fluorescence in situ hybridization

		HER2 FISH pharmDx™
		Non-amplified	Amplified	Total
HER2 CISH pharmDx™	Non-amplified	301	3	304
	Amplified	3	41	44
	Total	304	44	348

Two tailed 95% confidence intervals are based on the binomial distribution. Overall agreement: (342/348 × 100) = 98.3% (CI95: 96.5%; 99.3%), Positive agreement: (41/44 × 100) = 93.2% (CI95: 82.9%; 98.0%), Negative agreement: (301/304 × 100) = 99.0% (CI95: 97.4%; 99.7%) and Kappa: 0.92 (SE: 0.03)

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ISSN: 1472-6890

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