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  1. Case report

    Primary hyperoxaluria detected by bone marrow biopsy: case report

    Primary hyperoxaluria is a rare disease with an estimated prevalence of 1 to 3 cases per million. It is due to a hepatic enzyme deficiency responsible for an endogenous overproduction of oxalate. Oxalate cryst...

    F. Nachite, M. Dref, A. Fakhri and H. Rais

    BMC Clinical Pathology 2017 17:20

    Published on: 20 September 2017

  2. Research article

    Biochemical and histological alterations induced by the smoke of allethrin based mosquito coil on mice model

    Mosquito coil (MC) emits insecticide upon burning which provides limited protection against lethal mosquito borne diseases. However, apart from killing the insect, toxicities associated with the inhalation of ...

    M. Abdulla Al-Mamun, M. Ataur Rahman, M. Habibur Rahman, K.M.F. Hoque, Z. Ferdousi, Mohammad Nurul Matin and M. Abu Reza

    BMC Clinical Pathology 2017 17:19

    Published on: 30 August 2017

  3. Case report

    Primary breast angiosarcoma: a rare presentation of rare tumor – case report

    Primary breast angiosarcoma is defined as malignant proliferation showing endothelial differentiation. It is a very rare tumour (0.05% of primary mammary cancers), whose diagnosis can be difficult.

    Fayçal Abbad, Najat Cherif Idrissi, Btissam Fatih, Bouchra Fakhir, Jamal Drissi, Mouna Khouchani and Hanane Rais

    BMC Clinical Pathology 2017 17:17

    Published on: 29 August 2017

  4. Research article

    Accuracy of cervical cytology: comparison of diagnoses of 100 Pap smears read by four pathologists at three hospitals in Norway

    Cervical cancer can be prevented by early detection and treatment for precancerous lesions. Since 1995, there has been a national cervical cancer screening program in Norway, where women aged 25–69 years are r...

    Sveinung Wergeland Sørbye, Pål Suhrke, Berit Wallem Revå, Jannicke Berland, Ramona Johansen Maurseth and Khalid Al-Shibli

    BMC Clinical Pathology 2017 17:18

    Published on: 29 August 2017

  5. Case report

    Primary ovarian angiosarcoma in a 12- year -old girl: a case report of an exceptional localization in a context of limited resources country

    Ovarian sarcomas represent less than 1% of all ovary cancers and usually are frequent in adults. Primary angiosarcomas are exceptional in the ovaries within children.

    Tchin Darré, Abdoul-Samadou Aboubakari, Bingo K. N’Bortche, Akila Bassowa, Solange Adani-Ifé and Gado Napo-Koura

    BMC Clinical Pathology 2017 17:16

    Published on: 24 August 2017

  6. Case report

    Inflammatory myofibroblastic tumor of the lacrimal gland: case report of an exceptional location

    Inflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-...

    Adil Boudhas, Mohamed Allaoui, Fouad El Asri, Issam Rharrassi, Mohamed Reda El Ochi, Mohamed Tbouda, Hafsa Chahdi, Abderrahmane Al Bouzidi and Mohamed Oukabli

    BMC Clinical Pathology 2017 17:12

    Published on: 17 August 2017

  7. Research article

    Differential expression of CK20, β-catenin, and MUC2/5AC/6 in Lynch syndrome and familial colorectal cancer type X

    Hereditary non-polyposis colorectal cancer comprises Lynch syndrome and familial colorectal cancer type X (FCCTX). Differences in genetics, demographics and histopathology have been extensively studied. The pu...

    Stefan Haraldsson, Louise Klarskov, Mef Nilbert, Inge Bernstein, Jesper Bonde and Susanne Holck

    BMC Clinical Pathology 2017 17:11

    Published on: 17 August 2017

  8. Research article

    Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease

    The pathophysiology and outcome of meningococcal septic shock is closely associated with the plasma level of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating level of meningococcal DNA. Th...

    Berit Sletbakk Brusletto, Bernt Christian Hellerud, Else Marit Løberg, Ingeborg Løstegaard Goverud, Åshild Vege, Jens Petter Berg, Petter Brandtzaeg and Reidun Øvstebø

    BMC Clinical Pathology 2017 17:10

    Published on: 16 August 2017

  9. Case report

    A rare case of poorly differentiated thyroid carcinoma probably arising from a nodular goiter

    Some poorly differentiated thyroid carcinomas (PDTC) arise from pre-existing, well-differentiated carcinomas of follicular cell origin; however, others most likely arise de novo. The case of a PDTC adjacent to a ...

    Hironao Yasuoka, Yasushi Nakamura, Mitsuyoshi Hirokawa, Ken-ichi Yoshida, Kana Anno, Masayuki Tori and Masahiko Tsujimoto

    BMC Clinical Pathology 2017 17:9

    Published on: 2 June 2017

  10. Research article

    High expression of EphA3 (erythropoietin-producing hepatocellular A3) in gastric cancer is associated with metastasis and poor survival

    As the major subfamily of receptor tyrosine, erythropoietin-producing hepatocellular (Eph) receptor has been related to progression and prognosis in different types of tumors. However, the role and mechanism o...

    Baongoc Nasri, Mikito Inokuchi, Toshiaki Ishikawa, Hiroyuki Uetake, Yoko Takagi, Sho Otsuki, Kazuyuki Kojima and Tatsuyuki Kawano

    BMC Clinical Pathology 2017 17:8

    Published on: 27 April 2017

  11. Technical advance

    Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis

    The growth of tumor cells is accompanied by mutations in nuclear and mitochondrial genomes creating marked genetic heterogeneity. Tumors also contain non-tumor cells of various origins. An observed somatic mit...

    Paulo Refinetti, Christian Arstad, William G. Thilly, Stephan Morgenthaler and Per Olaf Ekstrøm

    BMC Clinical Pathology 2017 17:6

    Published on: 8 April 2017

  12. Case report

    Bone pathologic fracture revealing an unusual association: coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease

    The coexistence of Rosai-Dorfman disease (RDD) with Langerhans cell histiocytosis (LCH) is very rare, as to date only 17 cases have been reported in the english literature. The pathophysiology of this uncommon...

    Boubacar Efared, Asmae Mazti, Badarou Chaibou, Gabrielle Atsame-Ebang, Ibrahim Sory Sidibé, Layla Tahiri, Fatimazahra Erregad, Nawal Hammas, Abdelmajid El Mrini, Hinde El Fatemi and Laila Chbani

    BMC Clinical Pathology 2017 17:5

    Published on: 7 April 2017

  13. Research article

    Expression of human epidermal growth factor receptor 2 in bladder urothelial carcinoma

    Urothelial bladder carcinoma (UBC) is one of the most prevalent cancers in men worldwide. Human epidermal growth factor receptor 2 (HER2) expression has been detected in a wide range of urothelial carcinoma. D...

    Mohamed Reda El Ochi, Mohamed Oukabli, Elarbi Bouaiti, Hafsa Chahdi, Adil Boudhas, Mohamed Allaoui, Ahmed Ameur, Mohamed Abbar and Abderrahmane Al Bouzidi

    BMC Clinical Pathology 2017 17:3

    Published on: 4 April 2017

  14. Research article

    Peritumoral lymphatic vessel density and invasion detected with immunohistochemical marker D240 is strongly associated with distant metastasis in breast carcinoma

    Detection of vascular invasion by hematoxylin and eosin staining is the current pathological assessment practice to diagnose breast carcinoma. However, conventional hematoxylin and eosin staining failed to dis...

    Nur Fatiha Norhisham, Choi Yen Chong and Sabreena Safuan

    BMC Clinical Pathology 2017 17:2

    Published on: 10 February 2017

  15. Case report

    Mycetoma in a non-endemic area: a diagnostic challenge

    Mycetoma is a chronic granulomatous infectious disease caused by filamentous bacteria or by fungi. The disease is endemic in certain tropical and subtropical areas of the world but can be found elsewhere posin...

    Boubacar Efared, Layla Tahiri, Marou Soumana Boubacar, Gabrielle Atsam-Ebang, Nawal Hammas, El Fatemi Hinde and Laila Chbani

    BMC Clinical Pathology 2017 17:1

    Published on: 2 February 2017

  16. Research article

    Nucleic acid extraction from formalin-fixed paraffin-embedded cancer cell line samples: a trade off between quantity and quality?

    Advanced genomic techniques such as Next-Generation-Sequencing (NGS) and gene expression profiling, including NanoString, are vital for the development of personalised medicines, as they enable molecular disea...

    Caroline Seiler, Alan Sharpe, J. Carl Barrett, Elizabeth A. Harrington, Emma V. Jones and Gayle B. Marshall

    BMC Clinical Pathology 2016 16:17

    Published on: 14 November 2016

  17. Research article

    Oxidative profile of sickle cell patients in a Cameroonian urban hospital

    Sickle cell disease (SCD) is a class of hemoglobinopathy resulting from a single mutation in the ß-globin chain inducing the substitution of valine for glutamic acid at the sixth amino acid position which lead...

    Vicky Jocelyne Ama Moor, Constant Anatole Pieme, Bernard Chetcha Chemegne, Helene Manonji, Borgia Legrand Njinkio Nono, Corine Tchoula Mamiafo, Bruno Moukette Moukette, Francine Tankeu Nzufo and Asonganyi Tazoacha

    BMC Clinical Pathology 2016 16:15

    Published on: 21 September 2016

  18. Research article

    Dried blood spot omega-3 and omega-6 long chain polyunsaturated fatty acid levels in 7–9 year old Zimbabwean children: a cross sectional study

    Omega-3 long chain-polyunsaturated fatty acids (LC-PUFAs)–docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and eicosapentaenoic acid (EPA)– and omega-6 LC-PUFA arachidonic acid (ARA), are essential for ...

    Grace Mashavave, Patience Kuona, Willard Tinago, Babill Stray-Pedersen, Marshall Munjoma and Cuthbert Musarurwa

    BMC Clinical Pathology 2016 16:14

    Published on: 5 August 2016

  19. Research article

    Expression of podocalyxin-like protein is an independent prognostic biomarker in resected esophageal and gastric adenocarcinoma

    Podocalyxin-like protein (PODXL) is a cell surface transmembrane glycoprotein, the expression of which has been associated with poor prognosis in a range of malignancies. The aim of this study was to investiga...

    David Borg, Charlotta Hedner, Björn Nodin, Anna Larsson, Anders Johnsson, Jakob Eberhard and Karin Jirström

    BMC Clinical Pathology 2016 16:13

    Published on: 29 July 2016

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