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BMC Clinical Pathology


Section edited by Rui Henrique

This section considers articles on all aspect of histopathology and includes articles investigating microscopic examinations of tissues from biopsies or surgical specimens, we encourage submission of studies on biomarkers.

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  1. Content type: Case report

    Lymphoepithelial carcinoma is a tumor mostly diagnosed in the nasopharynx, but it has also been described in a variety of nonnasopharyngeal sites. It is extremely rare in the larynx and should be distinguished...

    Authors: Nawal Hammas, Najib Benmansour, Mohamed Nour-dine El Alami El Amine, Laila Chbani and Hind El Fatemi

    Citation: BMC Clinical Pathology 2017 17:24

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  2. Content type: Research article

    Intraoperative consultation is an important tool for the evaluation of the upper aerodigestive tract (UAT) malignancies. Although frozen section analysis is a preferred method of intra-operative consultation, ...

    Authors: Hania Naveed, Mariam Abid, Atif Ali Hashmi, Muhammad Muzammamil Edhi, Ahmareen Khalid Sheikh, Ghazala Mudassir and Amir Khan

    Citation: BMC Clinical Pathology 2017 17:25

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  3. Content type: Case report

    Solitary fibrous tumor is an uncommon spindle cell neoplasm of unknown origin. It has been reported in many anatomic sites, with a rare occurrence in the head and neck region. Solitary fibrous tumors of the pa...

    Authors: Meryem Rais, Amine Kessab, Zahra Sayad, Sanae El Mourabit, Redallah Zrarqi, Salma Benazzou, Malik Boulaadas and Nadia Cherradi

    Citation: BMC Clinical Pathology 2017 17:22

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  4. Content type: Case report

    Medulloepithelioma is a rare primitive neuroectodermal tumor of the central nervous system, usually developing in childhood. Due to its rarity, the optimal management is still unknown. The prognosis is poor, e...

    Authors: Nezha Oumghar, Fatima Ezzahra Hazmiri, Abdelhamid El Omrani, Hanane Rais and Mouna Khouchani

    Citation: BMC Clinical Pathology 2017 17:23

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  5. Content type: Case report

    Primary hyperoxaluria is a rare disease with an estimated prevalence of 1 to 3 cases per million. It is due to a hepatic enzyme deficiency responsible for an endogenous overproduction of oxalate. Oxalate cryst...

    Authors: F. Nachite, M. Dref, A. Fakhri and H. Rais

    Citation: BMC Clinical Pathology 2017 17:20

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  6. Content type: Research article

    Mosquito coil (MC) emits insecticide upon burning which provides limited protection against lethal mosquito borne diseases. However, apart from killing the insect, toxicities associated with the inhalation of ...

    Authors: M. Abdulla Al-Mamun, M. Ataur Rahman, M. Habibur Rahman, K.M.F. Hoque, Z. Ferdousi, Mohammad Nurul Matin and M. Abu Reza

    Citation: BMC Clinical Pathology 2017 17:19

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  7. Content type: Case report

    Primary breast angiosarcoma is defined as malignant proliferation showing endothelial differentiation. It is a very rare tumour (0.05% of primary mammary cancers), whose diagnosis can be difficult.

    Authors: Fayçal Abbad, Najat Cherif Idrissi, Btissam Fatih, Bouchra Fakhir, Jamal Drissi, Mouna Khouchani and Hanane Rais

    Citation: BMC Clinical Pathology 2017 17:17

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  8. Content type: Case report

    Ovarian sarcomas represent less than 1% of all ovary cancers and usually are frequent in adults. Primary angiosarcomas are exceptional in the ovaries within children.

    Authors: Tchin Darré, Abdoul-Samadou Aboubakari, Bingo K. N’Bortche, Akila Bassowa, Solange Adani-Ifé and Gado Napo-Koura

    Citation: BMC Clinical Pathology 2017 17:16

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  9. Content type: Case report

    Malignant Deciduoid Mesothelioma (MDM) is an extremely rare variant of epithelioid mesothelioma. It was first described in young females, in the peritoneum, and its relation with asbestos was not well defined.

    Authors: Mouna Khmou, Soumiya Echcharif, Rachad Kabbaj and Basma El Khannoussi

    Citation: BMC Clinical Pathology 2017 17:13

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  10. Content type: Case report

    Inflammatory myofibroblastic tumour (IMT) is a mesenchymal neoplasm of intermediate biological potential that may affect a wide range of anatomic sites but has a particular predilection for the lung and intra-...

    Authors: Adil Boudhas, Mohamed Allaoui, Fouad El Asri, Issam Rharrassi, Mohamed Reda El Ochi, Mohamed Tbouda, Hafsa Chahdi, Abderrahmane Al Bouzidi and Mohamed Oukabli

    Citation: BMC Clinical Pathology 2017 17:12

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  11. Content type: Research article

    Hereditary non-polyposis colorectal cancer comprises Lynch syndrome and familial colorectal cancer type X (FCCTX). Differences in genetics, demographics and histopathology have been extensively studied. The pu...

    Authors: Stefan Haraldsson, Louise Klarskov, Mef Nilbert, Inge Bernstein, Jesper Bonde and Susanne Holck

    Citation: BMC Clinical Pathology 2017 17:11

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  12. Content type: Case report

    Some poorly differentiated thyroid carcinomas (PDTC) arise from pre-existing, well-differentiated carcinomas of follicular cell origin; however, others most likely arise de novo. The case of a PDTC adjacent to a ...

    Authors: Hironao Yasuoka, Yasushi Nakamura, Mitsuyoshi Hirokawa, Ken-ichi Yoshida, Kana Anno, Masayuki Tori and Masahiko Tsujimoto

    Citation: BMC Clinical Pathology 2017 17:9

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  13. Content type: Research article

    As the major subfamily of receptor tyrosine, erythropoietin-producing hepatocellular (Eph) receptor has been related to progression and prognosis in different types of tumors. However, the role and mechanism o...

    Authors: Baongoc Nasri, Mikito Inokuchi, Toshiaki Ishikawa, Hiroyuki Uetake, Yoko Takagi, Sho Otsuki, Kazuyuki Kojima and Tatsuyuki Kawano

    Citation: BMC Clinical Pathology 2017 17:8

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  14. Content type: Case report

    The coexistence of Rosai-Dorfman disease (RDD) with Langerhans cell histiocytosis (LCH) is very rare, as to date only 17 cases have been reported in the english literature. The pathophysiology of this uncommon...

    Authors: Boubacar Efared, Asmae Mazti, Badarou Chaibou, Gabrielle Atsame-Ebang, Ibrahim Sory Sidibé, Layla Tahiri, Fatimazahra Erregad, Nawal Hammas, Abdelmajid El Mrini, Hinde El Fatemi and Laila Chbani

    Citation: BMC Clinical Pathology 2017 17:5

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  15. Content type: Research article

    Urothelial bladder carcinoma (UBC) is one of the most prevalent cancers in men worldwide. Human epidermal growth factor receptor 2 (HER2) expression has been detected in a wide range of urothelial carcinoma. D...

    Authors: Mohamed Reda El Ochi, Mohamed Oukabli, Elarbi Bouaiti, Hafsa Chahdi, Adil Boudhas, Mohamed Allaoui, Ahmed Ameur, Mohamed Abbar and Abderrahmane Al Bouzidi

    Citation: BMC Clinical Pathology 2017 17:3

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  16. Content type: Research article

    Detection of vascular invasion by hematoxylin and eosin staining is the current pathological assessment practice to diagnose breast carcinoma. However, conventional hematoxylin and eosin staining failed to dis...

    Authors: Nur Fatiha Norhisham, Choi Yen Chong and Sabreena Safuan

    Citation: BMC Clinical Pathology 2017 17:2

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  17. Content type: Case report

    Mycetoma is a chronic granulomatous infectious disease caused by filamentous bacteria or by fungi. The disease is endemic in certain tropical and subtropical areas of the world but can be found elsewhere posin...

    Authors: Boubacar Efared, Layla Tahiri, Marou Soumana Boubacar, Gabrielle Atsam-Ebang, Nawal Hammas, El Fatemi Hinde and Laila Chbani

    Citation: BMC Clinical Pathology 2017 17:1

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  18. Content type: Research article

    Calcifications of atherosclerotic plaques represent a controversial issue as they either lead to the stabilization or rupture of the lesion. However, the cellular key players involved in the progression of the...

    Authors: Silvia Fittipaldi, Francesco Vasuri, Alessio Degiovanni, Rodolfo Pini, Mauro Gargiulo, Andrea Stella, Gianandrea Pasquinelli, William G. Thilly and Elena V. Gostjeva

    Citation: BMC Clinical Pathology 2016 16:12

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  19. Content type: Research article

    Podocalyxin-like protein (PODXL) is a cell surface transmembrane glycoprotein, the expression of which has been associated with poor prognosis in a range of malignancies. The aim of this study was to investiga...

    Authors: David Borg, Charlotta Hedner, Björn Nodin, Anna Larsson, Anders Johnsson, Jakob Eberhard and Karin Jirström

    Citation: BMC Clinical Pathology 2016 16:13

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  20. Content type: Research article

    Effective management of trauma-related invasive fungal wound infections (IFIs) depends on early diagnosis and timely initiation of treatment. We evaluated the utility of routine staining, histochemical stains ...

    Authors: Sarah M. Heaton, Amy C. Weintrob, Kevin Downing, Bryan Keenan, Deepak Aggarwal, Faraz Shaikh, David R. Tribble and Justin Wells

    Citation: BMC Clinical Pathology 2016 16:11

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