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Table 3 Reference intervals for serum creatinine by age and sex

From: Reference intervals for serum cystatin C and serum creatinine in an adult sub-Saharan African population

Age (years)

N = 381

Serum creatinine (mg/dL)

Median (IQR)

2.5th percentile (90%CI)

97.5th percentile (90%CI)

p

< 20

Male: 9

1.09 (1.00–1.15)

0.80 (0.80–1.04)

1.18

< 0.001

Female: 14

0.76 (0.72–0.79)

0.66 (0.66–0.70)

0.88

All: 23

0.79 (0.75–1.08)

0.66 (0.66–0.70)

1.18

[20–30]

Male: 95

1.03 (0.94–1.12)

0.80 (0.70–0.85)

1.30 (1.29–1.35)

< 0.001

Female: 89

0.79 (0.71–0.87)

0.60 (0.54–0.61)

1.07 (1.01–1.28)

All: 184

0.91 (0.78–1.05)

0.61 (0.59–0.65)

1.30 (1.26–1.33)

[30–40]

Male: 40

1.06 (0.95–1.13)

0.75 (0.69–0.81)

1.29

< 0.001

Female: 31

0.73 (0.65–0.83)

0.57 (0.57–0.60)

1.26

All: 71

0.94 (0.74–1.08)

0.58 (0.57–0.62)

1.27 (1.22–1.32)

[40–50]

Male: 32

1.08 (0.99–1.17)

0.68 (0.68–0.74)

1.45

< 0.001

Female: 21

0.74 (0.69–0.90)

0.51 (0.51–0.66)

1.02

All: 53

0.99 (0.74–1.10)

0.61 (0.51–0.66)

1.38 (1.24–1.45)

≥ 50

Male: 18

1.17 (0.99–1.30)

0.79 (0.79–0.96)

1.52

< 0.001

Female: 32

0.85 (0.79–0.93)

0.60 (0.60–0.65)

1.05

All: 50

0.93 (0.81–1.06)

0.64 (0.60–0.66)

1.43 (1.33–1.52)

  1. CI confidence interval, IQR interquartile range. Some 90% confidence intervals are not presented due to the small number of participants in corresponding age groups. The Mann-Whitney U-test was used to compare males and females; the difference in the distribution of serum creatinine values between age-groups was not significant with the Kruskal-Wallis H-test (p = 0.491)