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Table 2 Reference intervals for serum cystatin C by age and sex

From: Reference intervals for serum cystatin C and serum creatinine in an adult sub-Saharan African population

Age (years)

N = 381

Serum cystatin C (mg/L)

Median (IQR)

2.5th percentile (90%CI)

97.5th percentile (90%CI)

p

< 20

Male: 9

0.9 (0.85–1.05)

0.7 (0.70–0.90)

1.1

0.003

Female: 14

0.75 (0.70–0.80)

0.6 (0.60–0.70)

0.9

All: 23

0.8 (0.70–0.90)

0.6 (0.60–0.70)

1.1

[20–30]

Male: 95

0.9 (0.80–1.0)

0.6 (0.60–0.70)

1.1 (1.10–1.10)

< 0.001

Female: 89

0.7 (0.70–0.80)

0.6 (0.50–0.60)

1.0 (0.90–1.00)

All: 184

0.8 (0.70–0.90)

0.6 (0.60–0.60)

1.1 (1.10–1.10)

[30–40]

Male: 40

0.9 (0.80–0.90)

0.7 (0.70–0.80)

1.0 (1.00–1.00)

0.001

Female: 31

0.8 (0.60–0.80)

0.5 (0.50–0.50)

1.0

All: 71

0.8 (0.80–0.90)

0.5 (0.50–0.58)

1.0 (1.00–1.00)

[40–50]

Male: 32

0.9 (0.80–0.98)

0.7 (0.70–0.70)

1.1

0.002

Female: 21

0.8 (0.70–0.90)

0.6 (0.60–0.70)

1.0

All: 53

0.8 (0.80–0.90)

0.6 (0.60–0.70)

1.0 (1.00–1.00)

≥ 50

Male: 18

1.0 (0.88–1.0)

0.7 (0.70–0.80)

1.2

0.125

Female: 32

0.9 (0.80–0.90)

0.6 (0.60–0.80)

1.1

All: 50

0.9 (0.80–1.00)

0.7 (0.60–0.73)

1.2 (1.10–1.20)

  1. CI confidence interval, IQR interquartile range. Some 90% confidence intervals are not presented due to the small number of participants in corresponding age groups. The Mann-Whitney U-test was used to compare the distribution of serum cystatin C values between males and females. The difference between age-groups was significant when using the Kruskal-Wallis H-test (p < 0.001)