Table 4 Clinicopathological variables and their correlation with immunohistochemical expression of HER2 and EGFR in ovarian metastases
Clinical Variables | HER2 Expression | EGFR Expression | ||||||
|---|---|---|---|---|---|---|---|---|
Total | Negative | Positive | P-value | Total | Negative | Positive | P-value | |
Total | 29 | 16 | 13 | – | 29 | 9 | 20 | – |
Age | ||||||||
≤ 55 | 19 | 10 | 9 | 1.000 | 19 | 6 | 13 | 1.000 |
> 55 | 10 | 6 | 4 | 10 | 3 | 7 | ||
Ovarian metastasis | ||||||||
Synchronous | 13 | 5 | 8 | 0.144 | 13 | 4 | 9 | 1.000 |
Metachronous | 16 | 11 | 5 | 16 | 5 | 11 | ||
Peritoneal metastasis | ||||||||
With | 15 | 13 | 2 | 0.001 | 15 | 4 | 11 | 0.700 |
Without | 14 | 3 | 11 | 14 | 5 | 9 | ||
Primary site | ||||||||
Colon | 20 | 11 | 9 | 1.000 | 20 | 6 | 14 | 1.000 |
Rectum | 9 | 5 | 4 | 9 | 3 | 6 | ||
Unilateral / bilateral ovarian metastasis | ||||||||
Unilateral | 10 | 1 | 9 | 0.001 | 10 | 4 | 6 | 0.675 |
Bilateral | 19 | 15 | 4 | 19 | 5 | 14 | ||