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Table 2 Clinicopathological variables and their correlation with immunohistochemical expression of HER2 in primary tumours

From: Clinical significance of HER2 and EGFR expression in colorectal cancer patients with ovarian metastasis

Clinicopathological variables

Ovarian metastasis CRC patients

 

Non-Ovarian metastasis CRC patients

Total

Positive [n (%)]

P′

 

Total

Positive [n (%)]

P″

Total

22

12 (54.5)

 

22

8 (36.4)

Age

  ≤ 55

15

9 (60.0)

0.652

 

8

1 (12.5)

0.167

  > 55

7

3 (42.9)

  

14

7 (50.0)

 

Primary tumour location

 Colon

17

9(52.9)

1.000

 

11

2 (18.2)

0.183

 Rectum

5

3 (60.0)

  

11

6 (54.5)

 

Differentiation

 High

2

2 (100)

0.476

 

1

1 (100)

0.364

 Mid-Low

19

9 (47.4)

  

21

7 (33.3)

 

 unknown

1

1 (100)

  

0

  

Positive lymph node

 0

5

4 (80.0)

0.150

 

8

2 (25.0)

0.853

 1~3

6

5 (83.3)

  

9

4(44.4)

 

  ≥ 4

9

3 (33.3)

  

5

2 (40.0)

 

 unknown

2

0 (0.0)

     

Tumour diameters

  ≤ 5 cm

11

7 (63.6)

0.653

 

15

5 (33.3)

1.000

  > 5 cm

9

4 (44.4)

  

7

3 (42.9)

 

 unknown

2

   

0

  

Vascular cancer embolus

 Yes

9

3 (33.3)

0.192

 

9

5 (55.6)

0.203

 No

13

9 (69.2)

  

12

3 (25.0)

 

 unknown

0

0 (0.0)

  

2

0 (0.0)