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Table 2 Clinicopathological variables and their correlation with immunohistochemical expression of HER2 in primary tumours

From: Clinical significance of HER2 and EGFR expression in colorectal cancer patients with ovarian metastasis

Clinicopathological variables Ovarian metastasis CRC patients   Non-Ovarian metastasis CRC patients
Total Positive [n (%)] P′   Total Positive [n (%)] P″
Total 22 12 (54.5)   22 8 (36.4)
Age
  ≤ 55 15 9 (60.0) 0.652   8 1 (12.5) 0.167
  > 55 7 3 (42.9)    14 7 (50.0)  
Primary tumour location
 Colon 17 9(52.9) 1.000   11 2 (18.2) 0.183
 Rectum 5 3 (60.0)    11 6 (54.5)  
Differentiation
 High 2 2 (100) 0.476   1 1 (100) 0.364
 Mid-Low 19 9 (47.4)    21 7 (33.3)  
 unknown 1 1 (100)    0   
Positive lymph node
 0 5 4 (80.0) 0.150   8 2 (25.0) 0.853
 1~3 6 5 (83.3)    9 4(44.4)  
  ≥ 4 9 3 (33.3)    5 2 (40.0)  
 unknown 2 0 (0.0)      
Tumour diameters
  ≤ 5 cm 11 7 (63.6) 0.653   15 5 (33.3) 1.000
  > 5 cm 9 4 (44.4)    7 3 (42.9)  
 unknown 2     0   
Vascular cancer embolus
 Yes 9 3 (33.3) 0.192   9 5 (55.6) 0.203
 No 13 9 (69.2)    12 3 (25.0)  
 unknown 0 0 (0.0)    2 0 (0.0)