Table 2 Association of HER2 status with clinicopathologic factors in breast cancer patients
Variables | HER2 + N = 105(%) | HER2- N = 472(%) | p |
|---|---|---|---|
Mean age ± SD | 48.6 ± 9.7 | 47.9 ± 11 | 0.568 |
Menopausal | Â | Â | 0.929 |
  < 50 years | 56(53.3) | 276(58.5) |  |
  ≥ 50 years | 49(46.7) | 196(41.5) |  |
Histologic type | |||
 IDC-NST | 91(86.7) | 393(83.3) | 0.666 |
 Lobular | 5(4.8) | 25(5.3) |  |
 Other | 9(8.5) | 54(11.4) |  |
Tumor grade | Â | Â | 0.007* |
 I | 13(13.8) | 83(21.1) |  |
 II | 70(74.5) | 224(57.0) |  |
 III | 11(11.7) | 86(21.8) |  |
ER status | Â | Â | 0.137 |
 Positive | 64(61.0) | 250(53.0) |  |
 Negative | 41(39.0) | 222(47.0) |  |
PR status | Â | Â | 0.396 |
 Positive | 47(44.8) | 190(40.3) |  |
 Negative | 58(55.2) | 282(59.7) |  |
ER/PR status | Â | Â | 0.134 |
 ER/PR+ | 68(64.8) | 268(56.8) |  |
 ER/PR- | 37(35.2) | 204(43.2) |  |