Table 1 Clinicopathologic characteristics of triple negative breast cancer
From: Prognostic significance of p16 & p53 immunohistochemical expression in triple negative breast cancer
n (%) | |
|---|---|
Age(years)° | 48.85 ± 11.49 |
Age groups | |
≤ 30 years | 5(3.3) |
31–50 years | 84(56) |
> 50 years | 61(40.7) |
Tumor size(Unit)° | 4.01 ± 1.99 |
Tumor stage/tumor size | |
T1 | 7(4.7) |
T2 | 116(77.3) |
T3/T4 | 27(18) |
Ki67 Index (%) | 46.89 ± 23.88 |
ki67 index groups | |
≤ 15% | 17(11.3) |
16–24% | 8(5.3) |
25–44% | 45(30) |
> 44% | 80(53.3) |
Nodal Status | |
Positive | 64(42.7) |
Negative | 86(57.3) |
Nodal Stage | |
No | 88(58.7) |
N1 | 30(20) |
N2 | 13(8.7) |
N3 | 19(12.7) |
Histological Subtypes | |
IDC | 127(84.7) |
Papillary | 6(4) |
Medullary | 1(0.7) |
Metaplastic | 14(9.3) |
Mixed | 2(1.3) |
Tumor Grade | |
Grade-I | 1(0.7) |
Grade-II | 19(12.7) |
Grade-III | 130(86.7) |
Lymphocytic infiltration | |
Absent | 15(10) |
Moderate | 110(73.3) |
Severe | 25(16.7) |
Lymhovascular Invasion | |
Present | 36(24) |
Absent | 114(76) |
Dermal Lymphatic invasion | |
Present | 10(6.7) |
Absent | 140(93.3) |
Type of Surgery | |
Modified radical mastectomy | 94(62.7) |
Simple mastectomy with sentinel lymph node dissection | 42(28) |
Wide local excision | 14(9.3) |
Necrosis | |
Absent | 21(14) |
Moderate | 90(60) |
Severe | 39(26) |
Fibrosis | |
Mild | 42(28) |
Moderate | 88(58.7) |
Severe | 20(13.3) |
Insitu component | |
Present | 58(38.7) |
Absent | 92(61.3) |
Pagetoid Spread | |
Present | 2(1.3) |
Absent | 148(98.7) |
Perinodal extension | |
Present | 30(20) |
Absent | 120(80) |
Triple negative phenotype | |
Basal | 16(10.7) |
Non-basal | 134(89.3) |
Adjuvant chemotherapy (n = 101) | |
Yes | 98(97) |
No | 3(3) |
Adjuvant radiation(n = 101) | |
Yes | 69(68.3) |
No | 32(31.7) |
Recurrence(n = 101) | |
Yes | 18(17.8) |
No | 83(82.2) |