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Fig. 8 | BMC Clinical Pathology

Fig. 8

From: Diagnostic guidelines for the histological particle algorithm in the periprosthetic neo-synovial tissue

Fig. 8

Non-implant wear, foreign particles/bone graft. a Absorbable surgical suture. Macrophage/giant cell reaction to deposits of absorbable suture material (H&E × 200), birefringent suture under polarized light in inset (× 200). b Fixation device (interference plastic poly-DL-lactide screw). Macrophage/giant cell reaction with palisading macrophages to plastic screw material implanted for anterior cruciate ligament reconstruction (H&E × 200), focal birefringence under polarized light in inset (× 200). c Scaffold composite material (carbon and polyester). Reactive fibrous tissue with embedded fragments of carbon fibers from a scaffold class anterior cruciate ligament (H&E × 200). d Joint spacer material. Macrophage reaction to silicone elastomer particles from a finger prosthetic implant (H&E × 200); particles are non-reactive under polarized light in inset (× 400). e Joint spacer material. Florid giant cell reaction to particles of porous polyurethaneurea (H&E × 200); particles are birefringent under polarized light in inset (× 400). f Visco-supplement reaction. Palisading macrophages and giant cell (black arrows) reaction to hyaluronan deposits (white arrow) (H&E × 100). g Skeletal substitute material. Demineralized bone matrix of allograft implant with intervening fibrous tissue (H&E × 200). h Skeletal substitute material. Porous tricalcium phosphate bone substitute (H&E × 200)

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