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Fig. 3 | BMC Clinical Pathology

Fig. 3

From: Diagnostic guidelines for the histological particle algorithm in the periprosthetic neo-synovial tissue

Fig. 3

Polyethylene (PE) particles. a Osteolysis with diffuse macrophage infiltrate containing PE micro-particles (H&E× 200), birefringent PE micro-particles under polarized light in the upper right inset (× 400), total ankle replacement implant in the lower right inset. b1. Oil red O positivity for macrophage cytoplasm containing PE micro- and submicron particles in a MoP TKA implant (× 200); b2. Oil red O positivity for macrophage cytoplasm containing tribocorrosion metallic particles in MoM HRA implant (× 200). c PE macroparticles (black arrows) in multinucleated giant cells (H&E × 200), birefringent particles under polarized light in the upper right inset (× 200), left unicompartmental knee implant with large area of PE abrasion/delamination (blue arrow) in the lower right inset. d PE supra-macroparticle lined by multinucleated giant cells in a case of failed total elbow prosthesis (H&E × 200), birefringent PE supra-macroparticle under polarized light in inset (× 200)

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