Accuracy of cervical cytology: comparison of diagnoses of 100 Pap smears read by four pathologists at three hospitals in Norway

Table 6 True positive, true negative, sensitivity and specificity for CIN2+ in different studies using ASC-US+ as cut-off

Study	TP	TN	FP	FN	SE (%)	SP (%)	AU (%)	PPV (%)	NPV (%)
Katki 2011 [10]	1 226	318 093	11 415	1 084	53.1²	96.5¹	78.4¹	9.7²	99.7¹
Dillner 2008 [15]	242	22 883	1 031	139	63.5¹	95.7²	79.6¹	19.0¹	99.4²
Castle 2012 [16]	136	18 190	926	260	34.3²	95.2²	64.7²	12.8¹	98.6¹
Szarewski 2008 [17]	256	236	444	17	93.8¹	34.7²	64.2²	36.6¹	93.3²
Sørbye 2011 [18]	48	92	77	8	85.7¹	54.4²	70.1²	38.4¹	92.0²
Total	1 908	359 494	13 893	1 508	55.9	96.3	76.1	12.1	99.6

TP true positive, TN true negative, FP false positive, FN false negative, SE sensitivity, SP specificity, AU = AUROC = accuracy = (SE+SP)/2, PPV positive predictive value, NPV negative predictive value, ASC-US+ = ASC-US, LSIL, ASC-H and HSIL, CIN2+ = CIN2, CIN3 and cancer
¹Significantly higher than the average (p<0.05)
²Significantly lower than the average (p<0.05)

ISSN: 1472-6890