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Table 5 True positive, true negative, sensitivity and specificity for CIN2+ per pathologists using ASC-H+ as cut-off

From: Accuracy of cervical cytology: comparison of diagnoses of 100 Pap smears read by four pathologists at three hospitals in Norway

Observer TP TN FP FN SE (%) SP (%) AU (%) PPV (%) NPV (%)
P1 (ref) 28 56 12 4 87.5 82.4 85.0 70.0 93.3
P2 30 48 20 2 93.81 70.62 82.2 60.0 96.01
P3 24 54 14 8 75.0 79.4 77.2 63.2 87.1
P4 23 65 3 9 71.9 95.61 83.8 88.51 87.8
P5 22 54 14 10 68.8 79.4 74.1 61.1 84.4
Mean (P2–P5) 24.8 55.3 12.8 7.3 77.4 81.3 79.4 68.2 88.8
  1. TP true positive, TN true negative, FP false positive, FN false negative, SE sensitivity, SP specificity, AU = AUROC = accuracy = (SE+SP)/2, PPV positive predictive value, NPV negative predictive value, ASC-H+ = ASC-H and HSIL, CIN2+ = CIN2, CIN3 and cancer
  2. 1Significantly higher than the average for P2–P5 (p<0.05)
  3. 2Significantly lower than the average for P2–P5 (p<0.05)