Accuracy of cervical cytology: comparison of diagnoses of 100 Pap smears read by four pathologists at three hospitals in Norway

Table 5 True positive, true negative, sensitivity and specificity for CIN2+ per pathologists using ASC-H+ as cut-off

Observer	TP	TN	FP	FN	SE (%)	SP (%)	AU (%)	PPV (%)	NPV (%)
P1 (ref)	28	56	12	4	87.5	82.4	85.0	70.0	93.3
P2	30	48	20	2	93.8¹	70.6²	82.2	60.0	96.0¹
P3	24	54	14	8	75.0	79.4	77.2	63.2	87.1
P4	23	65	3	9	71.9	95.6¹	83.8	88.5¹	87.8
P5	22	54	14	10	68.8	79.4	74.1	61.1	84.4
Mean (P2–P5)	24.8	55.3	12.8	7.3	77.4	81.3	79.4	68.2	88.8

TP true positive, TN true negative, FP false positive, FN false negative, SE sensitivity, SP specificity, AU = AUROC = accuracy = (SE+SP)/2, PPV positive predictive value, NPV negative predictive value, ASC-H+ = ASC-H and HSIL, CIN2+ = CIN2, CIN3 and cancer
¹Significantly higher than the average for P2–P5 (p<0.05)
²Significantly lower than the average for P2–P5 (p<0.05)

ISSN: 1472-6890