Biochemical and histological alterations induced by the smoke of allethrin based mosquito coil on mice model

BMC Clinical Pathology

Table 1 Inhalation effects of the mosquito coil smoke on biochemical parameters of blood

Parameters	Control	Inhalation treatment				Trend for p value
Parameters	Control	Group 1 (1/2 h)	Group 2 (1 h)	Group 3 (2 h)	Group 4 (3 h)	Trend for p value
ALT (U/L)	10.20 ± 1.32	11.03 ± 0.92	12.66 ± 2.44*	14.83 ± 2.86*	19.30 ± 2.00*	+0.001
AST (U/L)	41.10 ± 3.26	47.83 ± 4.18*	56.20 ± 4.10*	62.62 ± 5.8*	76. 96 ± 7.46*	+0.001
BUN (mg/dl)	9.66 ± 0.68	8.66 ± 0.75	8.46 ± 0.66	7.93 ± 0.41*	7.33 ± 0.51*	−0.001
Total protein (g/dl)	5.40 ± 0.32	5.13 ± 0.24	5.2 ± 0.23	4.8 ± 0.22*	4.32 ± 0.19*	−0.001
Cholesterol (mg/dl)	99.0 ± 4.68	105.3 ± 6.02	116.6 ± 4.93*	128.4 ± 9.45*	135.6 ± 8.11*	+0.001
LDL (mg/dl)	64.66 ± 3.51	69.43 ± 7.78	75.20 ± 5.0*	88.0 ± 6.88*	95.3 ± 8.16*	+0.001
Triglyceride(mg/dl)	86.8 ± 2.77	93.0 ± 5.36	96.66 ± 4.68*	100.3 ± 6.08*	112.58 ± 7.3*	+0.001

Data represent as averages ± SD (n = 6), significance was set at *P < 0.05 with respect to the control group

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