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Table 2 Univariate (log-rank) and multivariate (Cox proportional-harzards) analyses of the association between relapse free survival and clinicopathological factors including EphA3 expression

From: High expression of EphA3 (erythropoietin-producing hepatocellular A3) in gastric cancer is associated with metastasis and poor survival

Variables Univariate (log-rank) Multivariate
  5-years RFS (%) p HR 95% CI p
Age
  < 65 75.5 0.809    
  ≥ 65 74.5     
Gender
 Female 77.1 0.655    
 Male 74.4     
Main location
 Middle or Lower 80.1 0.001 1   
 Upper 55.8   1.684 0.937–3.029 0.082
WHO pathological type
 Differentiated 84 0.03 1   
 Undifferentiated 66.3   1.616 0.841–3.103 0.149
Depth of invasion
 T1 97.7 <0.001 1   
 T2,3,4 58.1   9.333 2.183–39.911 0.003
Lymph node metastasis
 Negative 94.7 <0.001 1   
 Positive 50.5   5.734 2.349–13.997 <0.001
EPHA3
 Low 82.0 0.014 1   
 High 67.0   1.313 0.705–2.447 0.391
HER2
 Negative 75.5 0.538    
 Positive 68.8     
  1. RFS relapse-free survival, HR harzard ratio, CI confidence interval; P < 0.05, statistically significant
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