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Table 2 Univariate (log-rank) and multivariate (Cox proportional-harzards) analyses of the association between relapse free survival and clinicopathological factors including EphA3 expression

From: High expression of EphA3 (erythropoietin-producing hepatocellular A3) in gastric cancer is associated with metastasis and poor survival

Variables

Univariate (log-rank)

Multivariate

 

5-years RFS (%)

p

HR

95% CI

p

Age

  < 65

75.5

0.809

   

  ≥ 65

74.5

    

Gender

 Female

77.1

0.655

   

 Male

74.4

    

Main location

 Middle or Lower

80.1

0.001

1

  

 Upper

55.8

 

1.684

0.937–3.029

0.082

WHO pathological type

 Differentiated

84

0.03

1

  

 Undifferentiated

66.3

 

1.616

0.841–3.103

0.149

Depth of invasion

 T1

97.7

<0.001

1

  

 T2,3,4

58.1

 

9.333

2.183–39.911

0.003

Lymph node metastasis

 Negative

94.7

<0.001

1

  

 Positive

50.5

 

5.734

2.349–13.997

<0.001

EPHA3

 Low

82.0

0.014

1

  

 High

67.0

 

1.313

0.705–2.447

0.391

HER2

 Negative

75.5

0.538

   

 Positive

68.8

    
  1. RFS relapse-free survival, HR harzard ratio, CI confidence interval; P < 0.05, statistically significant