|
Variables
|
Univariate (log-rank)
|
Multivariate
|
|---|
| |
5-years RFS (%)
|
p
|
HR
|
95% CI
|
p
|
|---|
|
Age
|
|
< 65
|
75.5
|
0.809
| | | |
|
≥ 65
|
74.5
| | | | |
|
Gender
|
|
Female
|
77.1
|
0.655
| | | |
|
Male
|
74.4
| | | | |
|
Main location
|
|
Middle or Lower
|
80.1
|
0.001
|
1
| | |
|
Upper
|
55.8
| |
1.684
|
0.937–3.029
|
0.082
|
|
WHO pathological type
|
|
Differentiated
|
84
|
0.03
|
1
| | |
|
Undifferentiated
|
66.3
| |
1.616
|
0.841–3.103
|
0.149
|
|
Depth of invasion
|
|
T1
|
97.7
|
<0.001
|
1
| | |
|
T2,3,4
|
58.1
| |
9.333
|
2.183–39.911
|
0.003
|
|
Lymph node metastasis
|
|
Negative
|
94.7
|
<0.001
|
1
| | |
|
Positive
|
50.5
| |
5.734
|
2.349–13.997
|
<0.001
|
|
EPHA3
|
|
Low
|
82.0
|
0.014
|
1
| | |
|
High
|
67.0
| |
1.313
|
0.705–2.447
|
0.391
|
|
HER2
|
|
Negative
|
75.5
|
0.538
| | | |
|
Positive
|
68.8
| | | | |
-
RFS relapse-free survival, HR harzard ratio, CI confidence interval; P < 0.05, statistically significant
