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Table 1 Correlation between EphA3 expression and clinicopathological features in gastric carcinoma

From: High expression of EphA3 (erythropoietin-producing hepatocellular A3) in gastric cancer is associated with metastasis and poor survival

Variables EphA3
  n
n = 202
Low
n = 111 (n, %)
High
n = 91 (n, %)
p value
Age
  < 65 97 60 (61.9) 37 (38.1) 0.067
  ≥ 65 105 51 (48.6) 54 (51.4)  
Gender
 Female 48 33 (68.8) 15 (31.3) 0.031
 Male 154 78 (50.6) 76 (49.4)  
Main location
 Middle or Lower 160 93 (58.1) 67 (41.9) 0.084
 Upper 42 18 (42.9) 24 (57.1)  
WHO pathological type
 Differentiated 99 39 (39.4) 60 (60.6) <0.001
 Undifferentiated 103 72 (69.9) 31 (30.1)  
Depth of invasion
 T1 87 59 (67.8) 28 (32.2) 0.002
 T2/3/4 115 52 (45.2) 63 (54.8)  
Lymph node metastasis
 Negative 113 74 (65.5) 39 (34.5) 0.001
 Positive 89 37 (41.6) 52 (58.4)  
Stage
 I 106 72 (67.9) 34 (32.1) <0.001
 II/III 96 39 (40.4) 57 (59.4)  
Distant recurrence
 Negative 152 91 (59.9) 61 (40.1) 0.021
 Positive 50 20 (40) 30 (60)  
Liver recurrence
 Negative 194 110 (56.7) 84 (43.3) 0.024
 Positive 8 1 (12.5) 7 (87.5)  
Peritoneal recurrence
 Negative 182 99 (54.4) 83 (45.6) 0.814
 Positive 20 12 (60) 8 (40)  
HER2
 Negative 186 107 (57.5) 79 (42.5) 0.017
 Positive 16 4 (25) 12 (75)  
  1. P < 0.05, statistically significant
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