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Table 1 Correlation between EphA3 expression and clinicopathological features in gastric carcinoma

From: High expression of EphA3 (erythropoietin-producing hepatocellular A3) in gastric cancer is associated with metastasis and poor survival

Variables

EphA3

 

n

n = 202

Low

n = 111 (n, %)

High

n = 91 (n, %)

p value

Age

  < 65

97

60 (61.9)

37 (38.1)

0.067

  ≥ 65

105

51 (48.6)

54 (51.4)

 

Gender

 Female

48

33 (68.8)

15 (31.3)

0.031

 Male

154

78 (50.6)

76 (49.4)

 

Main location

 Middle or Lower

160

93 (58.1)

67 (41.9)

0.084

 Upper

42

18 (42.9)

24 (57.1)

 

WHO pathological type

 Differentiated

99

39 (39.4)

60 (60.6)

<0.001

 Undifferentiated

103

72 (69.9)

31 (30.1)

 

Depth of invasion

 T1

87

59 (67.8)

28 (32.2)

0.002

 T2/3/4

115

52 (45.2)

63 (54.8)

 

Lymph node metastasis

 Negative

113

74 (65.5)

39 (34.5)

0.001

 Positive

89

37 (41.6)

52 (58.4)

 

Stage

 I

106

72 (67.9)

34 (32.1)

<0.001

 II/III

96

39 (40.4)

57 (59.4)

 

Distant recurrence

 Negative

152

91 (59.9)

61 (40.1)

0.021

 Positive

50

20 (40)

30 (60)

 

Liver recurrence

 Negative

194

110 (56.7)

84 (43.3)

0.024

 Positive

8

1 (12.5)

7 (87.5)

 

Peritoneal recurrence

 Negative

182

99 (54.4)

83 (45.6)

0.814

 Positive

20

12 (60)

8 (40)

 

HER2

 Negative

186

107 (57.5)

79 (42.5)

0.017

 Positive

16

4 (25)

12 (75)

 
  1. P < 0.05, statistically significant