Table 3 Association of HER2 expression with clinicopathological parameters of patients with UBC (n = 103)
From: Expression of human epidermal growth factor receptor 2 in bladder urothelial carcinoma
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
OR | IC 95% | P-Value | OR | IC95% | P-Value | |
Age | 1.01 | 0.96–1.06 | 0.77 | |||
Sex | ||||||
Women | 1 | |||||
Men | 1.29 | 0.14–11.7 | 0.82 | |||
Tumor size | ||||||
< 3 cm | 1 | 1 | ||||
≥ 3 cm | 2.35 | 0.6–9.26 | 0.22 | 0.73 | 0.12–4.46 | 0.74 |
Papillary architecture | ||||||
Absent | 1 | 1 | ||||
Present | 0.33 | 0.1–1.14 | 0.081 | 0.93 | 0.18–4.9 | 0.94 |
Carcinoma in situ | ||||||
Absent | 1 | 1 | ||||
Present | 0.01 | 0.01-6.4E + 19 | 0.84 | 0.73 | 0.01-6.2E + 17 | 0.81 |
Tumor grade | ||||||
Low | 1 | 1 | ||||
High | 7.5 | 1.9–29.9 | 0.004 | 5.67 | 1.1–30.2 | 0.042 |
Micropapillary differentiation | ||||||
Absent | 1 | 1 | ||||
Present | 4.04 | 0.34–48.3 | 0.27 | 1.7 | 0.1–30.4 | 0.72 |
T stage | ||||||
≤ pT1 | 1 | 1 | ||||
>pT1 | 5.06 | 1.4–17.8 | 0.012 | 2.58 | 0.55–12.2 | 0.29 |