Table 2 Hazard ratios for recurrence and death (M0, R0-1)

 Continuous

136 (72)

1.00 (0.98–1.02)

0.610

151 (104)

1.04 (1.02–1.06)

<0.001

1.05 (1.03–1.07)

<0.001

 Female

27 (12)

30 (22)

 Male

109 (60)

1.18 (0.63–2.19)

0.610

121 (82)

0.81 (0.50–1.29)

0.370

T stage

<0.001

0.043

0.010

0.511

 T1

18 (3)

19 (7)

 T2

27 (8)

2.14 (0.57–8.06)

0.263

1.53 (0.39–5.96)

0.538

30 (19)

2.09 (0.88–4.97)

0.097

1.53 (0.62–3.78)

0.357

 T3

77 (51)

6.92 (2.15–22.29)

0.001

3.72 (1.10–12.64)

0.035

86 (66)

3.27 (1.49–7.15)

0.003

1.79 (0.79–4.08)

0.164

 T4

14 (10)

8.52 (2.33–31.16)

0.001

3.52 (0.92–13.56)

0.067

16 (12)

3.71 (1.45–9.48)

0.006

1.98 (0.74–5.31)

0.175

 N0

50 (7)

53 (26)

 N1-3

86 (65)

9.89 (4.51–21.72)

<0.001

7.78 (3.24–18.71)

<0.001

98 (78)

2.56 (1.63–4.00)

<0.001

2.79 (1.67–4.66)

<0.001

 R0

103 (46)

113 (69)

 R1

33 (26)

2.89 (1.76–4.74)

<0.001

1.38 (0.79–2.41)

0.253

38 (35)

2.75 (1.80–4.20)

<0.001

2.07 (1.29–3.31)

0.003

 Low/Intermediate grade

49 (18)

56 (31)

 High grade

87 (54)

2.22 (1.30–3.79)

0.004

1.93 (1.09–3.42)

0.025

95 (73)

1.73 (1.13–2.63)

0.011

1.40 (0.88–2.20)

0.153

 Intestinal

94 (45)

106 (69)

 Diffuse/Mixed

42 (27)

1.57 (0.97–2.53)

0.064

45 (35)

1.35 (0.90–2.03)

0.149

 No

126 (63)

138 (94)

 Chemo-/radiotherapy

10 (9)

2.12 (1.05–4.28)

0.036

0.96 (0.45–2.06)

0.924

13 (10)

1.20 (0.62–2.30)

0.589

 Esophagus + EG junction

86 (49)

99 (69)

 Stomach

50 (23)

0.74 (0.45–1.22)

0.239

52 (35)

0.90 (0.60–1.34)

0.592

 Negative

20 (3)

24 (10)

 Positive

113 (67)

5.36 (1.68–17.06)

0.005

3.39 (1.01–11.35)

0.048

124 (92)

2.52 (1.31–4.85)

0.006

2.03 (1.04–3.98)

0.039