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Table 1 Associations of PODXL expression with clinicopathological factors

From: Expression of podocalyxin-like protein is an independent prognostic biomarker in resected esophageal and gastric adenocarcinoma

  Entire cohort PODXL neg PODXL pos  
n (%) n (%) n (%) p-value
  171 (100.0) 29 (17.0) 142 (83.0)  
Age
 ≤70 85 (49.7) 12 (41.4) 73 (51.4) 0.416
 >70 86 (50.3) 17 (58.6) 69 (48.6)
Sex
 Female 39 (22.8) 9 (31.0) 30 (21.1) 0.330
 Male 132 (77.2) 20 (69.0) 112 (78.9)
T stage
 T1 18 (10.5) 2 (6.9) 16 (11.3) 0.637
 T2 32 (18.7) 6 (20.7) 26 (18.3)
 T3 94 (55.0) 16 (55.2) 78 (54.9)
 T4 27 (15.8) 5 (17.2) 22 (15.5)
N stage
 N0 57 (33.3) 16 (55.2) 41 (28.9) 0.006
 N1 29 (17.0) 4 (13.8) 25 (17.6)
 N2 41 (24.0) 6 (20.7) 35 (24.6)
 N3 44 (25.7) 3 (10.3) 41 (28.9)
M stage
 M0 152 (88.9) 25 (86.2) 127 (89.4) 0.535
 M1 19 (11.1) 4 (13.8) 15 (10.6)
R classification
 R0 117 (68.4) 22 (75.9) 95 (66.9) 0.556
 R1 45 (26.3) 5 (17.2) 40 (28.2)
 R2 9 (5.3) 2 (6.9) 7 (4.9)
Differentiation grade
 Low grade 8 (4.7) 4 (13.8) 4 (2.8) 0.023
 Intermediate grade 52 (30.4) 10 (34.5) 42 (29.6)
 High grade 111 (64.9) 15 (51.7) 96 (67.6)
Lauren classification
 Intestinal 119 (69.6) 23 (79.3) 96 (67.6) 0.335
 Mixed 9 (5.3) 0 (0.0) 9 (6.3)
 Diffuse 43 (25.1) 6 (20.7) 37 (26.1)
Location
 Esophagus + EG junction 106 (62.0) 15 (51.7) 91 (64.1) 0.217
 Stomach 65 (38.0) 14 (48.3) 51 (35.9)
  1. R0 = no residual tumor (free resection margins according to pathology report), R1 = possible microscopic residual tumor (narrow or compromised resection margins according to pathology report), R2 = macroscopic residual tumor (according to surgery report)
  2. N1 = metastasis in 1–2 regional lymph nodes, N2 = metastasis in 3–6 regional lymph nodes, N3 = metastasis in 7 or more regional lymph nodes
  3. The dichotomized variable for age is based on the mean/median age, as shown in Additional file 1