Table 2 Histological patterns analyzed in hip replacement failures due to ALTR

Macrophagic Pattern

Macrophagic infiltrate (grade ≥ 1) without or with minimal evidence of interstitial and/or perivascular lymphocytic infiltrate (<grade 1)

Mixed Macrophagic and Lymphocytic Pattern w/wo Plasmacytic Component

Macrophagic (grade ≥ 1) and lymphocytic (grade ≥ 1) infiltrate

 Without Presence of Germinal Centers or Eosinophils

 With Presence of Germinal Centers or Eosinophils

Granulomatous Pattern

Any pattern with predominant presence of sarcoid-like granulomas

Lymphocytic Pattern

Interstitial and/or perivascular lymphocytic infiltrate without evidence of macrophagic infiltrate