TY - JOUR AU - Ricciardi, Benjamin F. AU - Nocon, Allina A. AU - Jerabek, Seth A. AU - Wilner, Gabrielle AU - Kaplowitz, Elianna AU - Goldring, Steven R. AU - Purdue, P. Edward AU - Perino, Giorgio PY - 2016 DA - 2016/02/27 TI - Histopathological characterization of corrosion product associated adverse local tissue reaction in hip implants: a study of 285 cases JO - BMC Clinical Pathology SP - 3 VL - 16 IS - 1 AB - Adverse local tissue reaction (ALTR), characterized by a heterogeneous cellular inflammatory infiltrate and the presence of corrosion products in the periprosthetic soft tissues, has been recognized as a mechanism of failure in total hip replacement (THA). Different histological subtypes may have unique needs for longitudinal clinical follow-up and complication rates after revision arthroplasty. The purpose of this study was to describe the histological patterns observed in the periprosthetic tissue of failed THA in three different implant classes due to ALTR and their association with clinical features of implant failure. SN - 1472-6890 UR - https://doi.org/10.1186/s12907-016-0025-9 DO - 10.1186/s12907-016-0025-9 ID - Ricciardi2016 ER -