TY - JOUR AU - Amaya, Clarissa N. AU - Bryan, Brad A. PY - 2015 DA - 2015/09/26 TI - Enrichment of the embryonic stem cell reprogramming factors Oct4, Nanog, Myc, and Sox2 in benign and malignant vascular tumors JO - BMC Clinical Pathology SP - 18 VL - 15 IS - 1 AB - The “stem cell theory of cancer” states that a subpopulation of cells with stem cell-like properties plays a central role in the formation, sustainment, spread, and drug resistant characteristics of malignant tumors. Recent studies have isolated distinct cell populations from infantile hemangiomas that display properties equivalent to aberrant progenitor cells, suggesting that, in addition to malignant tumors, benign tumors may also contain a stem cell-like component. SN - 1472-6890 UR - https://doi.org/10.1186/s12907-015-0018-0 DO - 10.1186/s12907-015-0018-0 ID - Amaya2015 ER -