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Table 1 Positive Predictive Values (PPV) of abnormal mucosal biopsies in infants being assessed for GIFA based on a single presenting gastrointestinal symptom based on 309/554 patients who presented with one symptom only

From: Histological findings in infants with Gastrointestinal food allergy are associated with specific gastrointestinal symptoms; retrospective review from a tertiary centre

  Number Percent Isolated increased mucosal eosinophil density PPV Any abnormal biopsy PPV
n n
Reflux/vomiting 117 37.9 % 19 16.2 % 53 45.3 %
Diarrhoea 72 23.3 % 30 41.7 % 51 70.8 %
Faltering growth 61 19.7 % 19 31.1 % 31 50.8 %
PR Bleeding 31 10.0 % 16 51.6 % 23 74.2 %
Haematemesis 7 2.3 % 1 14.3 % 4 57.1 %
Constipation 6 1.9 % 3 50.0 % 3 50.0 %
Feeding difficulties 4 1.3 % 0 0.0 % 0 0.0 %
Irritability 4 1.3 % 1 25.0 % 2 50.0 %
Anaemia 2 0.6 % 0 0.0 % 0 0.0 %
Hypoalbuminaemia 2 0.6 % 0 0.0 % 2 100.0 %
Abdominal distension 2 0.6 % 1 50.0 % 1 50.0 %
Recurrent Abdominal pain 1 0.3 % 0 0.0 % 1 100.0 %