Table 1 Positive Predictive Values (PPV) of abnormal mucosal biopsies in infants being assessed for GIFA based on a single presenting gastrointestinal symptom based on 309/554 patients who presented with one symptom only
Number | Percent | Isolated increased mucosal eosinophil density | PPV | Any abnormal biopsy | PPV | |
|---|---|---|---|---|---|---|
n | n | |||||
Reflux/vomiting | 117 | 37.9 % | 19 | 16.2 % | 53 | 45.3 % |
Diarrhoea | 72 | 23.3 % | 30 | 41.7 % | 51 | 70.8 % |
Faltering growth | 61 | 19.7 % | 19 | 31.1 % | 31 | 50.8 % |
PR Bleeding | 31 | 10.0 % | 16 | 51.6 % | 23 | 74.2 % |
Haematemesis | 7 | 2.3 % | 1 | 14.3 % | 4 | 57.1 % |
Constipation | 6 | 1.9 % | 3 | 50.0 % | 3 | 50.0 % |
Feeding difficulties | 4 | 1.3 % | 0 | 0.0 % | 0 | 0.0 % |
Irritability | 4 | 1.3 % | 1 | 25.0 % | 2 | 50.0 % |
Anaemia | 2 | 0.6 % | 0 | 0.0 % | 0 | 0.0 % |
Hypoalbuminaemia | 2 | 0.6 % | 0 | 0.0 % | 2 | 100.0 % |
Abdominal distension | 2 | 0.6 % | 1 | 50.0 % | 1 | 50.0 % |
Recurrent Abdominal pain | 1 | 0.3 % | 0 | 0.0 % | 1 | 100.0 % |