Tumor-specific expression of HMG-CoA reductase in a population-based cohort of breast cancer patients

BMC Clinical Pathology

Table 3 Multivariable analysis of risk for breast cancer related events in relation to HMGCR status in all patients

		95 % CI
	HR	Lower	Upper
HMGCR no staining	1.000
HMGCR weak expression	1.389	0.792	2.436
HMGCR moderate/strong expression	1.103	0.548	2.218
Invasive tumor size ≥ 21 mm or muscular/skin involvement	2.041	1.329	3.133
Axillary nodal involvement	1.427	0.946	2.153
Histological grade III	1.292	0.789	2.115
ER status	0.596	0.316	1.125
PgR status	0.740	0.448	1.223
Age ≥ 50 years	0.647	0.416	1.005
BMI ≥ 25 kg/m²	1.305	0.867	1.966
Preoperative smoker	1.289	0.811	2.050

ISSN: 1472-6890