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Table 1 Summary of KRAS mutations identified.

From: Experiences from treatment-predictive KRAS testing; high mutation frequency in rectal cancers from females and concurrent mutations in the same tumor

KRAS mutation

Amino acid change

*Number (%) mutations

Distribution colon/rectum

c.35G>A

p.Gly12 Asp

19 (33)

13/6

c.38G>A

p.Gly13Asp

12 (21)

8/5

c.35G>T

p.Gly12Val

10 (18)

4/6

c.34G>T

p.Gly12Cys

7 (12)

6/1

c.34G>A

p.Gly12Ser

5 (9)

1/4

c.35G>C

p.Gly12Ala

4 (7)

3/1

c.34G>C

p.Gly12Arg

-

-

  1. *Represents 53 tumors, including 3 with coexisting mutations