Table 4 Analysis of disagreements between molecular (sputum specimens and cultures) and phenotypical DST results
From: Performance of the Genotype® MTBDRPlus resistance patternSamara, Russian Federation
Molecular DST | Phenotypical DST | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Sputum | Culture | ||||||||
ID | GenoType® MTBDRplus pattern | ||||||||
RIF | INH | rpoB | katG | inhA | RIF | INH | RIF | INH | |
007–035 | S | S | WT | WT | WT | S | S | R | R |
007–060 | S | R | WT | Δwt S315T1 | WT | S | S | S | S |
007–069 | R | R | Δ8 S531L | WT | WT, C15T | S | S | R | S |
007–086 | R | R | Δ7,Δ8 | WT S315T1 | WT | S | S | S | S |
007–088 | R | R | Δ8 S531L | Δwt S315T1 | WT | S | S | S | R |
007–100 | S | S | WT | WT | WT | S | S | S | R |
007–121 | S | R | WT | WT S315T1 | WT | R* | R** | R | R |
007–127 | S | R | WT | WT S315T1 | WT | S | S | S | S |
007–141 | R | R | Δ8 S531L | WT S315T1 | Δwt C15T | S | R** | S | S |
007–149 | S | R | WT | Δwt S315T1 | WT | n/a | n/a | R | S |
007–153 | R | R | Δ8 S531L | Δwt S315T1 | WT | S | R*** | S | R |
007–166 | S | S | WT | WT | WT | n/a | n/a | R | R |