Skip to main content

Table 4 Positivity rates and patient characteristics by test ordered.*

From: Testing for hereditary thrombophilia: a retrospective analysis of testing referred to a national laboratory

 

Positivity

Fraction of positives which also had INR>1.3

Median Age

% Female

Protein S Functional

17.7%

21.2%

46

65.7%

Protein S Total Ag

4.8%

40.5%

47

63.0%

Protein S Free Ag

18.5%

25.0%

39

67.4%

Protein C Functional

13.7%

53.8%

46

65.4%

Protein C Total Ag

12.9%

33.3%

47

62.9%

Antithrombin Functional

7.5%

N/A

46

65.8%

Antithrombin Antigen

14.3%

N/A

46

65.3%

APC resistance

17.7%

N/A

46

65.7%

V Leiden mutation

12.3%

N/A

47

64.1%

Prothrombin G20210A mutation

4.9%

N/A

46

64.1%

  1. *Positivity for V Leiden and prothrombin mutations includes both heterozygotes and homozygotes; for the remaining assays it includes all results falling below the lower limit of the reported reference interval.